Carbamazepine and oxcarbazepine removal in pharmaceutical wastewater treatment plant using a mass balance approach: A case study

Dwivedi, Kshitiz; Morone, Amruta; Pratape, Vishwas; Chakrabarti, Tapan; Pandey, R.A.

doi:10.1007/s11814-017-0190-2

Cited by 12 publications

(3 citation statements)

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“…Real contaminated milieus are highly complex [4,248] and operate in 'harsh' environments consisting of many other chemicals. [246,[249][250][251][252] Furthermore, they co-exist under variable temperatures, pH values and a variety of organic contents (such as humic acid, [253] protein-like organic matter [254] or lipids and nucleic acids [255] ). These complications are enhanced by different ionic strengths, light intensity and flow rates.…”

Section: Selectivity Of Adsorbentsmentioning

confidence: 99%

Smart Adsorbents for Aquatic Environmental Remediation

Zare‬

Mudhoo

Khan

et al. 2021

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Section: Selectivity Of Adsorbentsmentioning

confidence: 99%

Smart Adsorbents for Aquatic Environmental Remediation

Zare‬

Mudhoo

Khan

et al. 2021

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“…There has been significant research effort to develop technologies to address CBZ degradation and removal in wastewater, among them reverse osmosis and adsorption (Dwivedi et al, 2017), nonthermal plasma (NTP) (Miklos et al, 2018;Wardenier et al, 2019), and wetlands (Chen et al, 2018). Filtration technology has been very effective in CBZ removal from wastewater (Rodriguez-Mozaz et al, 2015); however, there is the CBZ filtrate disposal problem.…”

Section: Introductionmentioning

confidence: 99%

Removal efficiency and energy consumption optimization for carbamazepine degradation in wastewater by electrohydraulic discharge

Gwanzura

Ramjugernath

Iwarere

2023

Water Environment Research

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OBJECTIVEThe treatment of recalcitrant emerging pollutants is a major concern in wastewater treatment. The purpose of this study was the optimisation of emerging recalcitrant pollutant degradation using carbamazepine as a representative pollutant. Investigations of the carbamazepine degradation in wastewater was carried out by manipulating discharge current, air flow rate, and initial concentration to maximise removal efficiency and minimise energy consumption.METHODThe study utilised a three factor at two levels factorial design with randomised central runs. Discharge current, air flow rate, and initial concentration were the independent variables while to removal efficiency and minimise energy consumption were the response variables. ANOVA analysis was performed on the data.RESULTSDischarge current, air flow rate, and initial concentration significantly impacted the removal efficiency to different degrees. However, for energy consumption, only current and air flow rate were the significant variables. The highest removal efficiency obtained was 93% ± 4% for 10 and 40 mg/L initial carbamazepine concentration after 10 minutes of plasma treatment at a current of 0.45 A and no air flow rate.CONCLUSIONThe reactor demonstrated the capability to treat high cyclic organic chemical contaminant concentration in wastewater with possible applications in pre‐concentrated wastewater remediation. However, there is still room for reactor design optimisation. One key area of focus is reducing treatment cost, which may be achieved theoretically, pending further experimental investigation, by introducing an alternating current power supply which can reduce energy consumption by 50‐60%.

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“…S1) is the most frequently used APIs for the treatment of epilepsy and other bipolar disorders [3]. CBZ, being recalcitrant, are highly resistant to conventional water and wastewater treatment processes and reported as an anthropogenic marker to indicate the pollution of the aquatic ecosystems [4,5]. Due to its persistent nature and longer half-life periods in environment, CBZ finds its presence in several water bodies in both developing and developed countries [6].…”

Section: Introductionmentioning

confidence: 99%

Transformation Products of Carbamazepine (CBZ) After Ozonation and their Toxicity Evaluation Using Pseudomonas sp. Strain KSH-1 in Aqueous Matrices

et al. 2018

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Carbamazepine (CBZ) is an anti-epileptic and anti-convulsant drug widely used for the treatment of epilepsy and other bipolar disorders. Ozone as an advanced oxidation process has been widely used for the degradation of CBZ resulting in the formation of transformation products (ozonides). The present research aims to isolate and identify potential microorganism, capable of degradation of CBZ and its transformation products. The cell viability and cytotoxicity of pure CBZ and their ozone transformation products were evaluated using the cells of sp. strain KSH-1 through cell viability assay tests. The cells metabolic activity was assessed at varying CBZ concentrations (~ 10-25 ppm, pure CBZ) and cumulatively for ozone transformation products. For pure CBZ, % cell viability decreases as CBZ concentration increases, while, in case of post-ozonated CBZ transformation products, the viability decreases initially and then increases upon exposure of ozone with a maximum cell viability of 97 ± 2.8% evaluated for 2 h post-ozonated samples.

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Carbamazepine and oxcarbazepine removal in pharmaceutical wastewater treatment plant using a mass balance approach: A case study

Cited by 12 publications

References 30 publications

Smart Adsorbents for Aquatic Environmental Remediation

Smart Adsorbents for Aquatic Environmental Remediation

Removal efficiency and energy consumption optimization for carbamazepine degradation in wastewater by electrohydraulic discharge

Transformation Products of Carbamazepine (CBZ) After Ozonation and their Toxicity Evaluation Using Pseudomonas sp. Strain KSH-1 in Aqueous Matrices

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