Abstract:The in vitro development of porcine corneal opacity induced by carbachol was monitored using a simple, specially constructed opacitometer. Corneas were used intact, without epithelium, or without endothelium, or stroma only. Solutions of carbachol were applied to both surfaces, to the epithelial surface only or to the endothelial surface only. When carbachol was applied either to both surfaces or to the epithelial surface only, there was a significant increase in opacity compared with controls in the order: bo… Show more
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