Carapa guianensis Aubl. (Meliaceae) oil associated with silk fibroin, as alternative to traditional surfactants, and active against larvae of the vector Aedes aegypti

Sarquis, Ícaro Rodrigues; Sarquis, Rosângela S. F. R.; Marinho, Victor H.S.; Neves, Fernando B.; Araújo, Inana F.; Damasceno, L. F.; Ferreira, Ricardo M. A.; Souto, Raiumundo N.P.; Carvalho, José Carlos Tavares; Ferreira, Irlon M.

doi:10.1016/j.indcrop.2020.112931

Cited by 19 publications

(20 citation statements)

References 51 publications

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“…Additionally, the hydrophobic interactions showed to be the main cause of interactions between SF and the fatty acid esters from A. murumuru fat. Similarly, previous reports by Sarquis (Sarquis et al 2020) proposed that the nanoemulsion containing 75% silk broin solution (2%), 5% fatty acid from C. guianensis Aubl. and 24% ethanol, shown be effective against A. aegypti (III instar larvae) with an LC 50 94.45 µg.mL − 1 at 24 h and 16.79 µg.mL − 1 at 48 h.…”

Section: Resultssupporting

confidence: 62%

“…The morphological damage in the larvae is the lethality effect of the nanoemulsions. Sarquis (Sarquis et al 2020) observed similar changes when using a nanoemulsion with free fatty acid from C. guianensis and silk broin, which was able to cause changes in the anal papilla and in the digestive and respiratory systems of A. aegypti larvae. Araújo (Araújo et al 2020) observed morphological damage in the respiratory siphon and anal papilla in A. aegypti larvae when using hexanic extract from the leaves of Acmella oleracea solubilized in silk broin.…”

Section: Resultsmentioning

confidence: 89%

“…The 10 mL solution contained 94% silk broin solution (2%), 1% active compounds and 5% of a mixture of ethanol and isopropanol (1:1). The emulsions were prepared according to Sarquis et al (2020), with slight modi cations.…”

Section: Preparation Of Ester/silk Broin Emulsionsmentioning

confidence: 99%

“…Emulsi cation methods using co-polymers and proteins have become a viable alternative for enhancing the dispersion of essential or xed oils in aqueous vehicles, as mosquitoes and other disease vectors need an aqueous environment to develop their life cycle (Echeverría and Albuquerque, 2019). Emulsions are formed and stabilized by surfactants or by amphiphilic polymers, which aim to reduce interfacial tension when adsorbed at the oil/water interface (Kaci et al 2017;Sarquis et al 2020). In comparison, silk broin is as an alternative to the various types of surfactants used in the formulation of emulsions, due to its low production cost, low cellular and environmental toxicity and high biodegradability, as well as being a biomaterial based on proteins (Ferreira et al 2017a).…”

Section: Introductionmentioning

confidence: 99%

“…Recently, our Group has developing biopesticides based on the use of silk broin as a vehicle co-polymeric. Araújo (Araújo et al 2020) evaluated the larvicidal action of the hydroethanolic, methanolic, and hexane extracts of Acmella oleracea leaves solubilized in silk broin (2%), and Sarquis (Sarquis et al 2020), that reported the use of free fatty acids from Carapa guianensis Aubl oil associated with silk broin, and its activity against A. aegpyti larvae, and found excellent LC 50 results after 48 h of 16.7 µg.mL − 1 .…”

Section: Introductionmentioning

confidence: 99%

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Development of an environmentally friendly formulation of silk fibroin associated with fatty acid from Astrocaryum murumuru Mart. fat, effective against larvae of the Aedes aegypti vector

Marinho

Neves

Jimenez

et al. 2021

Preprint

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The Aedes aegypti mosquito is a vector of several diseases, such as dengue, malaria and the Zika virus. Synthetic insecticides such as chlorpyrifos and chlorothalonil have been used for plague control, despite causing damage to the environment and to humans. It is therefore important to study natural active compounds with a low environmental impact. The present paper developed an environmentally friendly formulation of silk fibroin (SF) associated with fatty acid esters [ethyl (FAEE-SF), propyl (FAPE-SF) and butyl (FABE-SF)] from Astrocaryum murumuru Mart. fat, which was effective against Aedes aegypti 3th instar larvae. The FABE-SF nanoemulsion induced a higher mortality rate in the larvae of the A. aegypti after 48 h (LC50 = 18.92 µg / mL). The stabilities of the nanoemulsions were monitored for 21 days, and FABE-SF exhibited greater stability throughout the monitored period, with average particle, zeta and PDI values of around 217 ± 0.85 nm, -25.6 ± 3.24 mV and 0.338 ± 0.01, respectively. This paper reported the first effective action of fatty acid esters from A. murumuru Mart. associated with silk fibroin against A. aegypti. The FABE-SF solution also had a low hemolytic index, suggesting that treatment may be safe for animal and human use.

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Section: Resultssupporting

confidence: 62%

Section: Resultsmentioning

confidence: 89%

Section: Preparation Of Ester/silk Broin Emulsionsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Development of an environmentally friendly formulation of silk fibroin associated with fatty acid from Astrocaryum murumuru Mart. fat, effective against larvae of the Aedes aegypti vector

Marinho

Neves

Jimenez

et al. 2021

Preprint

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Anti-inflammatory potential of baicalein combined with silk fibroin protein in a zebrafish model (Danio rerio)

et al. 2022

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Baicalein (BA) is a flavonoid with wideranging pharmacological activity. However, its biological evaluation is hampered by its low solubility in aqueous medium, making forms of incorporation that improve its solubility necessary. In the present study, BA was combined with a solution of silk fibroin protein (SF), a biomaterial used too as a drug carrier, to evaluate the anti-inflammatory potential of this combination, in vivo, in an experimental model, zebrafish (Danio rerio). Baicalein-silk fibroin (BASF) improved the DPPH (2,2-diphenyl-1-picrylhydrazyl-hydrate) free radical scavenging rate (95%) in comparison with BA in solution. The acute toxicity study and histopathological analysis in zebrafish showed that BASF has low cytotoxic potential, except for the maxim dose of 2000 mg/kg. The use of BA in combination with SF enhanced the anti-inflammatory effect of flavonoids by inducing inflammatory peritoneal edema through carrageenan and achieved 77.6% inhibition of abdominal edema at a dose of 75 mg/kg. The results showed that the BASF, significantly increases the bioavailability and therapeutic effect of flavonoids and several results observed in this study may help in the development of new drugs.

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Valorization of Deodorizing Distillate Palm Oil Residue for Larvicidal Activity Against Aedes aegypti and Synergistic Effect of Their Free Fatty Acids

Ribeiro,

Lopes,

Marinho

et al. 2023

Waste Biomass Valor

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Increased consumption of palm oil results in more palm oil by-products. To meet environmental sustainability, deodorizing distillate palm oil (DDPO) also calls attention to diversifying its technological or commercial application. Because of this, the present work, to present new economic-scienti c alternatives for this by-product, aimed to evaluate the larvicide effect of DDPO, well as to investigate the synergistic effect of the combination of these fatty acid present in the composition of DDPO, against larvae of 3rd instar of Ae. aegypti. The DDPO larvicide assay showed a high mortality rate, with an LC 50 of 6.18 µg.mL − 1 at 24 h and 8.73 µg.mL − 1 at 48 h of treatment. In addition, the results of LC 50 , among saturated fatty foods and between the combination of fatty acid (myristic, lauric, stearic and oleic) with palmitic acid, were met positively by second-degree polynomial regression analysis. Finally, the study of molecular docking, corroborated, as potential inhibitors of the binding of juvenile hormones. Together, the results suggest that DDPO can be a potential natural larvicide agent, making it an alternative to the excessive use of synthetic insecticides, thus minimizing its impacts on the environment and promoting new technologies for the use of this palm oil by-product.

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Carapa guianensis Aubl. (Meliaceae) oil associated with silk fibroin, as alternative to traditional surfactants, and active against larvae of the vector Aedes aegypti

Cited by 19 publications

References 51 publications

Development of an environmentally friendly formulation of silk fibroin associated with fatty acid from Astrocaryum murumuru Mart. fat, effective against larvae of the Aedes aegypti vector

Development of an environmentally friendly formulation of silk fibroin associated with fatty acid from Astrocaryum murumuru Mart. fat, effective against larvae of the Aedes aegypti vector

Anti-inflammatory potential of baicalein combined with silk fibroin protein in a zebrafish model (Danio rerio)

Valorization of Deodorizing Distillate Palm Oil Residue for Larvicidal Activity Against Aedes aegypti and Synergistic Effect of Their Free Fatty Acids

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