Caracterización de los pacientes con bacteriemia por Staphylococcus aureus resistente a la meticilina en un hospital militar de alta complejidad

Objective There is paucity of data on the epidemiological, microbiological, and clinical characteristics of patients admitted with infective endocarditis (IE) in the Bronx, New York. Patient and methods We conducted a retrospective study at Jacobi Medical Center, a tertiary care hospital in the Bronx. All adult patients who were hospitalized with a primary diagnosis of new-onset IE between January 1st, 2010 and September 30th, 2020 were included. The primary outcome was in-hospital mortality. A logistic regression model was used to identify baseline variables associated with in-hospital mortality. Results 182 patients were included in this analysis (female sex: 38.5%, median age: 54 years). 46 patients (25.3%) reported intravenous drug use. 153 patients (84.1%) had positive blood cultures. Staphylococcus aureus (S. aureus) was the most common isolated pathogen (45.1% of monomicrobial IE). Nearly half of the cases secondary to S. aureus were methicillin resistant staphylococcus aureus (MRSA) (34/69). 164 patients (90.1%) were diagnosed with native valve IE. The mitral valve was involved in 32.4% of patients followed by the aortic valve (19.8%). The in-hospital mortality was 18.1%. The mortality was higher in the cohort 2010–2015 compared to the cohort 2016–2020 (22.1% vs 14.6%). MRSA IE was the only variable found to have significant association with in-hospital death. Conclusion S. aureus was the most common causative agent and MRSA accounted for about half of the S. aureus IE cases. The incidence of IE in patients with intravenous drug use increased over time, while the median age decreased. The in-hospital death rate was higher in 2010–2015 compared to 2016–2020.

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Caracterización de los pacientes con bacteriemia por Staphylococcus aureus resistente a la meticilina en un hospital militar de alta complejidad

Cited by 2 publications

References 31 publications

Epidemiologic and clinical characteristics of infective endocarditis: a single-center retrospective study in the Bronx, New York

Epidemiologic and clinical characteristics of infective endocarditis: a single-center retrospective study in the Bronx, New York

Correction to the article published in 2022: Epidemiologic and clinical characteristics of infective endocarditis: a single-center retrospective study in the Bronx, New York

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