Caracterización de aislamientos invasivos de S. pneumoniae, H. influenzae y N. meningitidis en América Latina y el Caribe: SIREVA II, 2000-2005

Gabastou, Jean-Marc; Agudelo, Clara Inés; Brandileone, Maria Cristina de Cunto; Castañeda, Elizabeth; Lemos, Ana Paula Silva de; Fabio, José Luís Di

doi:10.1590/s1020-49892008000700001

Cited by 50 publications

(47 citation statements)

References 81 publications

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“…Seventy-eight percent of the cases were reported in Brazil or Chile. Of the total, 69% were serogroup B and 26% serogroup C. Serogroups Y and W135 comprised approximately 2% of the cases [4]. In Panama, according to the SIREVA II regional report, the data recorded show that between the years 2000-2005, serogroup B was responsible for 68% of the cases, with the majority in children younger than 14 years (63.6%) [4].…”

Section: Introductionmentioning

confidence: 99%

Epidemiology of meningococcal disease in the Panamanian pediatric population, 1998-2008

Guevara

Luciani

Montesdeoca-Melían

et al. 2010

J Infect Dev Ctries

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Introduction: Worldwide public health authorities report 500,000 cases of invasive meningococcal disease with 50,000 deaths per year and 10-15% of sequelae in people affected. This study describes the epidemiology, microbiology, and clinical presentation of this disease in the Panamanian pediatric population. Methodology: The discharge of patients with a meningococcal invasive disease diagnosis was reviewed in the statistical database and archives of the Hospital del Niño. Results: A total of 32 discharges with a meningococcal disease diagnosis were reported during the study period (1998)(1999)(2000)(2001)(2002)(2003)(2004)(2005)(2006)(2007)(2008). Ninety-one percent (n/N = 29/32) were confirmed as meningitis. The mean age of patients was 4.1 ± 4.6 years. The incidence in the period of the study was 0.25/100,000. Infants younger than one year old presented the highest incidence rate and number of cases. Four deaths were reported, three of which occurred in the group of 10-14 years and one in the group of 1-4 years. The overall fatality rate was 12.5%. The serogroup of the causative agent, Neisseria meningitidis, was documented in 30 of the 32 cases, with serogroup B the most frequent (66.7%). Ninetypercent (18/20) of serogroup B were isolated in the first five years of study. Serogroup C was identified in 8 of the 12 cases during the period

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Section: Introductionmentioning

confidence: 99%

Epidemiology of meningococcal disease in the Panamanian pediatric population, 1998-2008

Guevara

Luciani

Montesdeoca-Melían

et al. 2010

J Infect Dev Ctries

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“…Nascimento KA et al -Epidemiological profile of meningococcal disease in Minas Gerais, [2000][2001][2002][2003][2004][2005][2006][2007][2008][2009] Serogroup B of N. meningitidis has been predominant since 1988 in Rio de Janeiro, followed by serogroup C. Since the 1990s, Brazil had a progressive increase in serogroup C outbreaks 1,[11][12][13] .…”

Section: Resultsmentioning

confidence: 99%

Epidemiological profile of meningococcal disease in the State of Minas Gerais and in the Central, North, and Triângulo Mineiro regions, Brazil, during 2000-2009

Nascimento

Miranzi

Scatena

2012

Rev. Soc. Bras. Med. Trop.

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INTRODUCTION: Infection by Neisseria meningitidis, termed as meningococcal disease, can cause meningococcal meningitis and septicemia with or without meningitis. Meningococcal disease is endemic in Brazil and has a high potential to cause large-scale epidemics; therefore, it requires the immediate notification of cases to the Information System for Notifiable Diseases (SINAN) in Brazil. The aim of this study was to describe an epidemiological profile using data from notified and confirmed cases in the State of Minas Gerais, Brazil, from January 2000 to December 2009, obtained from the investigation records of individuals with meningitis registered with SINAN. METHODS: This was a retrospective, population-based study. Descriptive analysis of the data was made using the simple and relative frequencies of the categorical variables in the investigation records. RESULTS: There were 1,688 confirmed patients in Minas Gerais of which 45.5% lived in the Central, North, and Triângulo Mineiro regions. The highest frequencies of cases were in the 1-4-years age group (26.3%), males (54.7%), caucasian (36.4%), and lived in an urban area (80%). In the patients with specified education, 650 (60.9%) patients had secondary education. Serogrouping of meningococci had been performed in 500 (29.6%) patients by age and gender; 285 (57%) belonged to serogroup C, 67 (13.4%) were in the 1-to 4-years age group, and 168 (33.6%) were male. CONCLUSIONS: The epidemiological profiles of patients in the Central, North, and Triângulo Mineiro regions were not significantly different from the profile of patients in Minas Gerais.

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“…También es necesario informar al personal médico y paramédico sobre el impacto de la enfermedad, su adecuado reconocimiento, así como sobre la importancia de colaborar con los sistemas de vigilancia y control en salud pública 9,29 .…”

Section: Discussionunclassified

“…En los últimos 40 años se han presentado epidemias y brotes en toda la región, los cuales se han asociado con los serogrupos B, C, Y y W, de acuerdo con el comportamiento característicamente impredecible de la enfermedad [8][9][10] . El más reciente de estos fue reportado en Chile, donde se documentó aumento de la proporción de casos causados por el serogrupo W asociado con aumento de casos de meningococemia (67%) y letalidad general del 25% 11,12 .…”

Section: Introductionunclassified

Epidemiología de la enfermedad por meningococo en Colombia

Vélez-van-Meerbeke

Medina-Silva²,

Besada-Lombana³

et al. 2016

Infectio

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ResumenObjetivos: Describir la situación epidemiológica de la enfermedad meningocócica en Colombia. Material y métodos: Estudio descriptivo que recopiló información de diferentes fuentes pertenecientes al Sistema Nacional de Vigilancia en Salud Pública. Las variables fueron analizadas de forma descriptiva y se calcularon las tasas de incidencia cuando los datos requeridos estuvieron disponibles. Resultados: Durante el periodo 2005-2011 se notificaron 1.065 casos, lo que representó un promedio anual de incidencia de 0,36/100.000 habitantes. De estos, se confirmaron tan solo el 46%, lo que apunta a la existencia de una importante brecha de notificación y confirmación. La mayor incidencia se encontró en menores de un año (5,4-6,9/100.000 habitantes) y el 50% de los casos se presentaron en menores de 10 años. Discusión: La Neisseria meningitidis serogrupo B representó la mayor proporción de los aislamientos; sin embargo, en los últimos años los serogrupos Y y C han tenido un repunte importante. Los síntomas fueron en general inespecíficos, el curso de la enfermedad fue rápido y la letalidad fue alta (13,3%). Conclusiones: Existe la necesidad de mejorar las herramientas disponibles para la vigilancia. Las acciones preventivas deben estar dirigidas a lactantes y niños, con protección contra los serogrupos Y y C. Es necesaria la investigación de estrategias contra el serogrupo B.Palabras clave: Meningitis meningocócica; Epidemiología; Salud Pública; Vacunación Epidemiology of meningococcal disease in Colombia AbstractObjectives: The purpose of this paper was to describe the epidemiology of meningococcal disease in Colombia. Materials and methods: This was a descriptive study based on data from various sources in the National Surveillance System. The variables were analysed descriptively and the incidence rates were estimated when the required data were available. Results: During the 2005-2011 period, 1,065 cases were reported, which represented an annual mean incidence of 0.36/100.000 inhabitants. Of these, only 46% were confirmed, which reveals a gap between reporting and confirmation. The greatest incidence was observed in infants younger than one year (5.4-6.9/100,000) and 50% of the cases occurred in children under 10 years of age. Discussion: Neisseria meningitidis serogroup B represented the greatest proportion of isolates; however, serogroups Y and C have been increasing recently. The symptoms were non-specific, the course of the disease was rapid and the lethality high (13.3%). Conclusions: There is a need to improve the available tools for diagnosis and surveillance. Prevention must be oriented toward infants, toddlers and children including protection against serogroups C and Y. Research into strategies for prevention against serogroup B is also necessary. Keywords: Meningococcal meningitis; Epidemiology; Public Health; Vaccination IntroducciónLa enfermedad meningocócica es causada por la bacteria Neisseria meningitidis (meningococo). Debido a su diversidad genética, esta bacteria se subclasifica en serogrupo...

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Caracterización de aislamientos invasivos de S. pneumoniae, H. influenzae y N. meningitidis en América Latina y el Caribe: SIREVA II, 2000-2005

Cited by 50 publications

References 81 publications

Epidemiology of meningococcal disease in the Panamanian pediatric population, 1998-2008

Epidemiology of meningococcal disease in the Panamanian pediatric population, 1998-2008

Epidemiological profile of meningococcal disease in the State of Minas Gerais and in the Central, North, and Triângulo Mineiro regions, Brazil, during 2000-2009

Epidemiología de la enfermedad por meningococo en Colombia

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