Caracterização físico-química de ossos liofilizados de origem bovina e humana

Gália, Carlos Roberto; Rosito, Ricardo; Mello, Tielle Müller de; Diesel, Cristiano Valter; Moreira, Luís Fernando

doi:10.1590/s0100-69912009000200013

Cited by 6 publications

(4 citation statements)

References 8 publications

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“…We performed simulations to prove the operation of the device using samples of orthodontic plaster cylinders simulating human bone encased in porcine skin. This kind of skin has been recommended for studies since it has physiological, histological, and biochemical similarities and density close to that of human skin [ 26 ]. Each plaster cylinder was built with only water and plaster, 2 cm in diameter and 7.5 cm in height.…”

Section: Methodsmentioning

confidence: 99%

“…Next, we used the femur poultry bones since, in addition to representing the first bird order associated with humans, such birds have relatively long femur bones [ 27 ]. Moreover, we also used bones from the porcine proximal phalanx, given their remarkable similarity to human bone tissue [ 28 ] and bones from cattle femurs since they satisfactorily reproduce aspects of human anatomy [ 29 ].…”

Section: Methodsmentioning

confidence: 99%

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A method based on non-ionizing microwave radiation for ancillary diagnosis of osteoporosis: a pilot study

et al. 2022

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Background Osteoporosis is a condition characterized by low bone mineral density, which typically leads to fractures and reduced quality of life. Currently, diagnostic devices used to assess this condition (e.g., dual-energy X-ray absorptiometry) are very costly, making it infeasible to meet the demand for testing in most countries. Therefore, we proposed a preclinical validation of a prototype called Osseus in an attempt to enhance osteoporosis screening tests and alleviate their costs. Osseus is a device developed to assist bone mineral density classification. It integrates a microcontroller into other peripheral devices to measure the attenuation at the middle phalanx of the middle finger, with two antennas operating at the 2.45 GHz frequency. Results We conducted tests with plaster, poultry, and porcine bones. A comparison of the measurements of the original and mechanically altered samples demonstrated that the device can handle the complexity of the tissues within the bone structure and characterize its microarchitecture. Conclusions Osseus is a device that has been preliminarily validated. Ionising radiation needed for DXA tests is replaced by non-ionising microwave electromagnetic radiation. Osseus enables early detection of osteoporosis, reduces costs, and optimizes high-complexity testing referrals. There is a lack of validation studies with the reference/gold standard that are currently under development.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

A method based on non-ionizing microwave radiation for ancillary diagnosis of osteoporosis: a pilot study

et al. 2022

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show abstract

“…We have performed simulations to prove the operation of the device using samples of orthodontic plaster cylinders simulating human bone and encased in porcine skin. This kind of skin has been recommended for studies since it has physiological, histological, biochemical similarities and density akin to human skin [29]. Each plaster cylinder was built with only water and plaster, 2 cm in diameter and 7.5 cm in height.…”

Section: Proof Of Conceptmentioning

confidence: 99%

Osseus: A Method Based on Artificial Intelligence and Electromagnetic Waves for Ancillary Diagnosis of Osteoporosis

Albuquerque

Cruz

Carvalho

et al. 2021

Preprint

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Background: Osteoporosis is characterized by low bone mineral density, which causes fractures and compromises people's quality of life. Diagnostic devices for assessing this health condition, such as Dual Energy X-ray Absorptiometry (DXA), are very costly. Therefore, it is impracticable to meet the demand for tests in Brazil's 5,568 municipalities. Given that, we proposed a pre-clinical validation of a prototype developed to aid bone mineral density classification. Thus, Osseus integrates a microcontroller with other peripheral devices to measure the electromagnetic permittivity at the middle phalanx of the middle finger, with two antennas operating in the 2.45 GHz frequency range. Using Artificial Intelligence to identify risk factors alongside signal attenuation measurement indicates the need for DXA. Results: We conducted tests with plaster, Galliformes, and porcine bones. Comparison of the measurements of the original and mechanically altered samples have demonstrated that the device can handle the complexity of the tissues within the bone structure and characterize its microarchitecture. Conclusions: Osseus is a prototype and has been preliminarily validated. There is a lack of validation studies with the reference/gold standard that are currently under development. Osseus enables early detection of osteoporosis, reduces costs, and optimizes high-complexity testing referrals.

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“…The area of biomaterials points to major advances. Examples are the use of hydroxyapatite for surface coating, the use of alternative bone graft as humans or bovine lyophilized to assist in cases of bone loss, as well as the development of multidisciplinary techniques for bone regeneration, as in the case of VascuBone Project [102][103][104].…”

Section: Perspectives To the Futurementioning

confidence: 99%

Hip Arthroplasty

Gália¹,

Ribeiro²,

Diesel³

et al. 2019

Hip Surgeries

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Hip replacement is one of the most performed surgical procedures in orthopedic hip surgery. Through this surgery, the patient returns to most of his normal life and a life without pain. The primary indication for a hip arthroplasty remains osteoarthritis (OA). OA is a degenerative disease that affects synovial joints. A successful surgery is always preceded by good planning. The planning in turn takes into account the analysis of the patient and his physical examination and the radiological image. But also, the surgical planning must take into account another important factor, the choice of the surgical approach. In this chapter, the authors script a revision on the history of hip arthroplasty, total hip arthroplasty approaches, implant types, complications associated with hip arthroplasty, outcomes, and perspectives to the future. We wish you a good reading.

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Caracterização físico-química de ossos liofilizados de origem bovina e humana

Cited by 6 publications

References 8 publications

A method based on non-ionizing microwave radiation for ancillary diagnosis of osteoporosis: a pilot study

A method based on non-ionizing microwave radiation for ancillary diagnosis of osteoporosis: a pilot study

Osseus: A Method Based on Artificial Intelligence and Electromagnetic Waves for Ancillary Diagnosis of Osteoporosis

Hip Arthroplasty

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