Abstract:PEREIRA DE PÁDUA, R. A. Structural and functional characterization of Trypanosoma cruzi fumarate hydratase isoforms. 119 f. Thesis (Doctorate). School of Pharmaceutical Sciences of Ribeirão Preto -University of São Paulo, Ribeirão Preto, 2014.Trypanosoma cruzi is a flagellate protozoan parasite that infects humans and causes Chagas disease, a tropical neglected disease that affects millions of people worldwide. Fumarate hydratases (FH), or fumarases, are enzymes responsible for the reversible stereo-specific h… Show more
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