CAR Macrophages: a promising novel immunotherapy for solid tumors and beyond
Jialin Lu,
Yuqing Ma,
Qiuxin Li
et al.
Abstract:With the advent of adoptive cellular therapy, chimeric antigen receptor (CAR)-T cell therapy has gained widespread application in cancer treatment and has demonstrated significant efficacy against certain hematologic malignancies. However, due to the limitations of CAR-T cell therapy in treating solid tumors, other immune cells are being modified with CAR to address this issue. Macrophages have emerged as a promising option, owing to their extensive immune functions, which include antigen presentation, powerfu… Show more
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