Capnography for Adults

Stock, M.

doi:10.1016/s0749-0704(18)30093-9

Cited by 26 publications

(13 citation statements)

References 26 publications

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“…Studies have demonstrated in adults that the current ETCO 2 sampling devices may underestimate arterial CO 2 by 5-10 mm Hg, based on the pathophysiology of the patient. 16,37,38 This underestimation may be greater in children, who physiologically have a higher respiratory rate, which may be further worsened with BPD. Additionally, the dilutional effect of any concurrent oxygen supplementation during ETCO 2 measurement could also have played a role.…”

Section: Discussionmentioning

confidence: 99%

Neurodevelopmental Outcomes at Two Years of Age for Premature Infants Diagnosed With Neonatal Obstructive Sleep Apnea

Bandyopadhyay

Harmon

Slaven

et al. 2017

Journal of Clinical Sleep Medicine

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Study Objectives: Neurocognitive deficits have been shown in school-aged children with sleep apnea. The effect of obstructive sleep apnea (OSA) on the neurodevelopmental outcome of preterm infants is unknown. Methods: A retrospective chart review was performed for all preterm infants (< 37 weeks) who had neonatal polysomnography (PSG) and completed neurodevelopmental assessment with the Bayley Scales of Infant and Toddler Development, 3rd Edition, between 2006 to 2015 at Riley Hospital. Exclusion criteria included grade IV intraventricular hemorrhage, tracheostomy, cyanotic heart disease, severe retinopathy of prematurity, craniofacial anomalies, or central and mixed apnea on PSG. Sleep apnea was defined as an apnea-hypopnea index (AHI) > 1 event/h. Regression analyses were performed to find a relationship between PSG parameters and cognitive, language, and motor scores. Results: Fifteen patients (males: n = 10) were eligible for the study. Median postmenstrual age at the time of the PSG was 41 weeks (37-46). Median AHI for the cohort was 17.4 events/h (2.2-41.3). Median cognitive, language, and motor scores were 90 (65-125), 89 (65-121), and 91 (61-112), respectively. Mean end-tidal CO2 (median 47 mm Hg ) negatively correlated with cognitive scores (P = .01) but did not significantly correlate with language or motor scores. AHI was not associated with cognitive, language, or motor scores. Conclusions: The median score for cognitive, language, and motor scores for preterm infants with neonatal OSA were within one standard deviation of the published norm. Mean end-tidal CO2, independent of AHI, may serve as a biomarker for predicting poor cognitive outcome in preterm infants with neonatal OSA. Commentary: A commentary on this article appears in this issue on page 1233. Keywords: obstructive sleep apnea, polysomnography, infant, newborn Citation: Bandyopadhyay A, Harmon H, Slaven JE, Daftary AS. Neurodevelopmental outcomes at two years of age for premature infants diagnosed with neonatal obstructive sleep apnea.

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Section: Discussionmentioning

confidence: 99%

Neurodevelopmental Outcomes at Two Years of Age for Premature Infants Diagnosed With Neonatal Obstructive Sleep Apnea

Bandyopadhyay

Harmon

Slaven

et al. 2017

Journal of Clinical Sleep Medicine

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“…As these intermittent reaffirmations of lung isolation were of short duration (15 sec or less), complete lung deflation and occlusion of the bronchial blocker's central lumen as a result of the 200 mL/min gas sampling from the Datex monitor or the anesthesia machine was not encountered [3].…”

Section: Discussionmentioning

confidence: 99%

Using the capnograph to confirm lung isolation when using a bronchial blocker

Fisicaro

Maguire

Armstead

2010

Journal of Clinical Anesthesia

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“…6 In obese postoperative patients with obstructive sleep apnea, the mean arterial to ETCO 2 gradient was 8.3 mm Hg. 7 Even in patients with diverse neuromuscular and pulmonary disorders, the ETCO 2 during sleep was found to underestimate a simultaneous arterial CO 2 by ≥ 10 mm Hg in only 21% of the readings.…”

Section: S C I E N T I F I C I N V E S T I G a T I O N Smentioning

confidence: 96%

Polysomnographic Determinants of Nocturnal Hypercapnia in Patients with Sleep Apnea

Jaimchariyatam

Dweik²,

Kaw³

et al. 2013

Journal of Clinical Sleep Medicine

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mass index or the apnea-hypopnea index, indices usually associated with daytime hypercapnia in the obesity hypoventilation syndrome. 9 We therefore sought to determine whether the nocturnal ETCO 2 could refl ect physiologic characteristics of obstructive sleep apnea not addressed by the apnea-hypopnea index or body mass index, and therefore expand its indication beyond the hypoventilation syndromes. For instance, contributors to the development of an elevated daytime arterial CO 2 BRIEF SUMMARY Current knowledge/Study Rationale: Although end-tidal CO 2 determination is reliable and accurate, its current application in polysomnography has been limited to the evaluation of sleep disordered breathing in children, the quantitative assessment of sleep hypoventilation syndromes, or as an adjunct signal for detection of sleep apnea. The aim of our study was to investigate whether end-tidal CO 2 is associated with polysomnographic or demographic characteristics in patients with sleep apnea. Study Impact: Daytime and nocturnal end-tidal CO 2 are signifi cantly related to post apnea duration, and to a lesser extent to apnea duration and age, but not to the apnea-hypopnea index or the body mass index. End-tidal CO 2 monitoring can therefore be expanded beyond its current applications in apnea detection and hypoventilation syndromes, to its use as a marker of the pathophysiology, severity, and ventilatory burden of sleep apnea, all features that may be inadequately captured by the apnea-hypopnea index.

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Capnography for Adults

Cited by 26 publications

References 26 publications

Neurodevelopmental Outcomes at Two Years of Age for Premature Infants Diagnosed With Neonatal Obstructive Sleep Apnea

Neurodevelopmental Outcomes at Two Years of Age for Premature Infants Diagnosed With Neonatal Obstructive Sleep Apnea

Using the capnograph to confirm lung isolation when using a bronchial blocker

Polysomnographic Determinants of Nocturnal Hypercapnia in Patients with Sleep Apnea

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