Capnocytophaga canimorsus meningitis in a newborn: an avoidable infection

Rosenman, Jane R.; Reynolds, Janet K.; Kleiman, Martin B.

doi:10.1097/01.inf.0000048949.21724.78

Cited by 22 publications

(12 citation statements)

References 13 publications

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“…Consequences of C. canimorsus infections include sepsis, endocarditis, meningitis, disseminated intravascular coagulation, and hemolytic uremic syndrome. In addition to dog bites, some cases of C. canimorsus septicemias have been associated with cat bites and scratches, and others have been acquired through mucosal contact with dog or cat saliva [62,71,84,85,109].…”

Section: Diseases From Animal Bites and Scratches Or Other Contactmentioning

confidence: 99%

Important emerging bacterial zoonotic infections affecting the immunocompromised

2005

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-The immunocompromised are at particular risk for infection with zoonotic diseases. Persons can be temporarily immunocompromised due to pregnancy or developmental stage (i.e. infants); longer-term or permanent states of immunosuppression can occur as a result of immunosuppressive treatment following cancer or organ transplant, or from infectious diseases, such as AIDS. The focus of this review article is on emerging bacterial zoonotic diseases that are of particular concern among the immunocompromised. Factors that affect disease emergence can include factors such as human demographics and behavior; technology and industry; economic development and land use; international travel and commerce; microbial adaptation and change; and breakdown of public health measures. The immunocompromised need to take precautions when engaging in seemingly normal activities such as food preparation; caring for companion animals; and recreational or occupational activities. The immunocompromised are not only more susceptible to infection, but often suffer more serious sequelae as a result of infection. This review article provides an overview of the major foodborne, respiratory, and vector-borne bacterial pathogens that affect the immunocompromised. The major categories of immunodeficiency are described. In addition, measures that can be taken to prevent infection, including the role of health education, are discussed.

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Section: Diseases From Animal Bites and Scratches Or Other Contactmentioning

confidence: 99%

Important emerging bacterial zoonotic infections affecting the immunocompromised

2005

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“…Ungewöhnlich ist zweifellos die Erkrankung eines Neugeborenen mit einer C.-canimorsus-Meningitis [37]. In der betroffenen Familie gab es drei Hunde.…”

Section: Diskussionunclassified

Letal verlaufende Capnocytophaga-canimorsus-Sepsis nach Hundebiss

Handrïck¹,

Schwede²,

Steffens³

2010

Med Klin

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A 56-year-old man was bitten by a dog. 8 days later he was admitted to a hospital because of severe deterioration of his clinical situation. He developed the clinical picture of fulminant sepsis. In spite of aggressive intensive care therapy the patient died 24 hours later. Capnocytophaga canimorsus was identified from initial blood cultures. This gram-negative rod is part of the normal oral flora of dogs and cats. It can be spread to humans by bites, licking or scratches and causes severe infections, especially in persons with special risk factors (splenectomy, alcoholism). The mortality rate in the published cases is 25-30%.

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“…In the postnatal period, mucous membrane exposure to canine saliva (via facial licking) has been associated with C. canimorsus meningitis in one newborn. 19 Review of perinatal literature Human Capnocytophaga species, while of low virulence, have potential to be invasive ( Table 1). The risk is greater in the infant than mother; of 15 neonatal cases reported, 8/15 women were asymptomatic or had minimal symptoms.…”

Section: Microbiologymentioning

confidence: 99%