‘Capiture’ plants with interesting biological activities: a case to go

Tittikpina, Nassifatou Koko; Atakpama, Wouyo; Pereki, Hodabalo; Nasim, Muhammad Jawad; Ali, Wesam; Fontanay, Stéphane; Nana, Frédéric; Ejike, Chukwunonso E.C.C.; Kirsch, Gilbert; Duval, Raphaël E.; Chaimbault, Patrick; Karou, Simplice Damintoti; Batawila, Komlan; Akpagana, Koffi; Jacob, Claus

doi:10.1515/chem-2017-0024

Cited by 7 publications

(5 citation statements)

References 18 publications

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“…Pterocarpus erinaceus contains tannins, flavonoids, phenols and saponins. It has also been confirmed that its stem bark possesses a broad antimicrobial spectrum including Bacillus subtilis, Pseudomonas aeruginosa, Escherichia coli, Staphylococcus aureus and Candida albicans [27][28][29]. Tittikpina et al [29] isolated four compounds from the plant, i.e.…”

Section: Discussionmentioning

confidence: 99%

Ethnobotanical Study of Plants Used in Traditional Treatment of Diarrhoea in Humans and Cattle in Two Regions of Ivory Coast

Karim

Bolou

N’docho

et al. 2020

EJMP

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Ethnopharmacological Relevance: An ethnobotanical survey was conducted in three regions of the country (two rural and one urban), using a questionnaire focussing on anti-diarrheal therapeutic habits. Methodology: Information about the plants has been recorded (local name, organs or part(s) of the plant used, therapeutic indications, harvesting methods, methods of administration, side effects, etc.). Collection of the plants was done in collaboration with traditional practitioners and identification of the specimens was conducted at the National Floristic Center (Ivory coast). During the ethnobotanical survey, twelve traditional healers and nine breeders were interviewed which all declared to treat diarrhoea with plants. During this survey, twenty-seven species belonging to eighteen different families of plants were reported for anti-diarrhoeal use in humans or animals. They were all harvested on the field and a herbarium of each species was prepared in duplicate, one stored at the National Floristic Centre of the Felix Houphouët-Boigny University and the other at the Pasteur Institute of Ivory coast. Results: Decoction was the most common mode of preparation used by practionioners and the oral route remained also the main way of administration of plants by healers. These plants are also used in other countries for the same or other purpose. Conclusion: This study shows that traditional medicinal plants play an important role in the treatment of diarrhoea in Ivory coast. It provides basis for future studies to assess, biological and chemical potential of these plants.

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Section: Discussionmentioning

confidence: 99%

Ethnobotanical Study of Plants Used in Traditional Treatment of Diarrhoea in Humans and Cattle in Two Regions of Ivory Coast

Karim

Bolou

N’docho

et al. 2020

EJMP

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“…The plant, 'Pterocarpus erinaceus (Fabaceae)' is a tree found in the most tropical areas of Africa [20,21]. In West Africa, its leaves, stem bark, and roots have been reported as highly use for traditional remedies against inflammation, ulcer, pain in the joints, malaria-fever, and bacterial infections [22].Various scientific studies had confirm Pterocarpus erinaceus ability to exhibit several biological activities as well as identification of several components.…”

Section: Introductionmentioning

confidence: 99%

Protective Efficiency of Pterocarpus erinaceus Leaves Extract in Carbon-tetrachloride-induced Hepatic and Hematological Injuries in Rats

Mohammed

Mhya

et al. 2023

JALSI

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Aims: Chemical toxicity is one of the major leading causes of tissues injuries, which impair the tissue’s ability to maintain normal physiological functions. Pterocarpus erinaceus is a medicinal plant use as traditional remedy for the treatment of several disorders associated with tissues injuries. This study therefore aimed at investigating tissues protective efficiency of Pterocarpus erinaceus leaves extract in carbon-tetrachloride-induced hepatic and hematological injuries in rats. Materials and Methods: Leaves of Pterocarpus erinaceous after collection were air-dried and pulverized. It was extracted with methanol and the methanolic extracts were used. Acute toxicity and hepatoprotective studies against CCl4 toxicity were conducted. Rats were grouped into; Group 1: Normal control (liquid paraffin, vehicle 1ml.kg), Group 2: Negative control (received 1ml/kg CCl4), Group 3: Positive control (received 1ml/kg CCl4 +100ml/kg Silymarin), Group 4-6: Extract treated rats (received 1ml/kg CCl4 + varied doses of Extracts at 100, 200, and 400mg/kg body weight of rats). The treatment was done daily via oral means for 14 days. Results: The results of the acute toxicity study showed Pterocarpus erinaceus extract safe with LD50 greater than 5000mg/kg body weight. This study reveals Pterocarpus erinaceus able to ameliorate CCl4 toxicity by minimizing damage to hepatic and hematological tissues. Histological study of the rats’ hepatic cells further unveils the protective ability of the plant extract against severity of CCl4-mediate hepatic architectural damage. Conclusion: Pterocarpus erinaceus leaves possess components with tissue-protective properties hence the need to harness it for utilization.

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“…The prioritization process led to highly ranked plants that were further investigated biologically [ 12 ]. Following their footsteps, we have also developed a model to identify the most promising plants from a list of species reported after an ethnobotanical survey for possible treatment of infectious diseases in Togo [ 13 ]. The ethnobotanical study involving a semi-structured individual interview with 53 traditional healers from the Tchamba district of Togo led to identifying 43 different species effective against infectious diseases [ 13 , 14 ].…”

Section: Introductionmentioning

confidence: 99%

“…Following their footsteps, we have also developed a model to identify the most promising plants from a list of species reported after an ethnobotanical survey for possible treatment of infectious diseases in Togo [ 13 ]. The ethnobotanical study involving a semi-structured individual interview with 53 traditional healers from the Tchamba district of Togo led to identifying 43 different species effective against infectious diseases [ 13 , 14 ]. This methodology, named CAPITURE (Computer Aided Products Identification from Traditional Usage Records) method, predicted Pterocarpus erinaceus and Daniellia oliveri as the most promising plants out of 43 plant species employed by traditional healers to treat infectious diseases [ 13 ].…”

Section: Introductionmentioning

confidence: 99%

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Daniellia oliveri (Rolfe) Hutch and Dalziel: Antimicrobial Activities, Cytotoxicity Evaluation, and Phytochemical Identification by GC-MS

et al. 2022

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During a previous study that identified plants used in traditional medicine in Togo to treat infectious diseases, Daniellia oliveri was specifically reported to treat intertrigo and candidiasis. Consequently, to explore the anti-infective potential of this plant, we investigated the antibacterial and the antifungal activity of the plant’s parts, as well as the cytotoxic activities of raw extracts and subsequent fractions, and the chemical composition of the most active fractions. In order to evaluate the antimicrobial activity, MICs were determined using the broth dilution method. Then, the most active fractions were evaluated for cytotoxicity by using normal human cells (MRC-5 cells) via the MTT assay. Finally, the most active and not toxic fractions were phytochemically investigated by GC-MS. Interestingly, all the raw extracts and fractions were active against the bacteria tested, with MICs ranging from 16 µg/mL to 256 µg/mL, while no antifungal activity was observed at 256 µg/mL, the highest tested concentration. Moreover, no toxicity was observed with most of the active fractions. The subsequent chemical investigation of the most interesting fractions led to identifying terpenes, phytosterols, phenolic compounds, and fatty acids as the main compounds. In conclusion, this study demonstrated that D. oliveri possesses valuable antibacterial activities in accordance with traditional use.

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‘Capiture’ plants with interesting biological activities: a case to go

Abstract: Abstract:The investigation of

Cited by 7 publications

References 18 publications

Ethnobotanical Study of Plants Used in Traditional Treatment of Diarrhoea in Humans and Cattle in Two Regions of Ivory Coast

Ethnobotanical Study of Plants Used in Traditional Treatment of Diarrhoea in Humans and Cattle in Two Regions of Ivory Coast

Protective Efficiency of Pterocarpus erinaceus Leaves Extract in Carbon-tetrachloride-induced Hepatic and Hematological Injuries in Rats

Daniellia oliveri (Rolfe) Hutch and Dalziel: Antimicrobial Activities, Cytotoxicity Evaluation, and Phytochemical Identification by GC-MS

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