Capillary electrophoretic studies on the migration behavior of cationic solutes and the influence of interactions of cationic solutes with sodium dodecyl sulfate on the formation of micelles and critical micelle concentration

Interaction of cefadroxyl monohydrate with hexadecyltrimethyl ammonium bromide and sodium dodecyl sulfate

“…The physico-chemical interaction of drugs with surfactant micelles can be understood as an approximation for their interactions with biological surface. Although a number of studies on the interaction of surfactants with different drugs are reported in the literature [7][8][9], to the best of our knowledge, very little is known about the interaction of ionic surfactants with cefadroxyl monohydrate (CFM). CFM, a broad-spectrum cephalosporin antibiotic, is used especially in the treatment of respiratory, urinary tract, skin, and skin structure infections and is intended for oral administration.…”

Flow manipulation for sweeping with a cationic surfactant in microchip capillary electrophoresis

“…When surfactant is added to the sample solution, the surfactant molecules possibly form ion pairs with analytes, because surfactants, such as SDS and TTAB, are good ion-pairing reagents. Anionic SDS molecules can form strong ion pairs with cationic solutes [29], and even with neutral analytes [30]. The interaction between analytes and surfactant monomers can be very strong and should not be ignored, since ion pairing will affect the effective mobility of the analytes [31,32].…”

“…Then the swept plug length is determined by Equation 7. where k s is the retention factor when the surfactant above the CMC is in the sample solution. The retention factor is a linear function of the surfactant concentration when the micellar concentrations are low [30,34]. (8) where P mw is the partition coefficient of a solute between the micelles and the water, ν̃ is the molar volume of the micelles, and C T is the total concentration of the surfactant.…”

A highly sensitive colorimetric sensor for adrenaline detection based on organic molecules-functionalized gold nanoparticles

“…Low levels of adrenaline have been found in patients with Parkinson's disease [6,7]. So far, various methods have been reported for the quantitative determination of adrenaline, such as fluorescence [8][9][10], electrochemistry [6,[11][12][13], capillary electrophoresis (CE) [14,15], liquid chromatography (LC) [16][17][18], and chemiluminescence (CL) [19][20][21] detection. However, most of these methods are limited because of their high cost, tedious operation, and even dependence on the pre-treatment of extraction or derivatization.…”