Capillary electrophoresis with led-induced native fluorescence detection for determination of isoquinoline alkaloids and their cytotoxicity in extracts of Chelidonium majus L

Kulp, Maria; Bragina, Olga; Kogerman, Priit; Kaljurand, Mihkel

doi:10.1016/j.chroma.2011.06.016

Cited by 41 publications

(16 citation statements)

References 33 publications

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“…One paper reported the use of native UV‐LED‐induced fluorescence (LEDIF) for the sensitive analysis of seven alkaloids in the medicinal herb, Chelidonium majus L. . This light source was operated at 280 nm and the emission was at the range 341–600 nm.…”

Section: Methods Developmentmentioning

confidence: 99%

Capillary electrophoresis of natural products: 2011–2012

et al. 2014

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Bioactive natural products are major sources of lead compounds for drug discovery and pharmaceutical development, therefore, innovative and current separation and characterization techniques are important for these compounds. Here, CE methods applied for the analysis of natural products published during 2011-2012 are reviewed. This is an updated version of an earlier review paper in this journal, which highlighted developments during 2006-2010. The major method developments over the review period centered on derivatization, chiral analysis, modes of detection, stacking or on-line sample concentration, and sample preparation (predominantly using extraction methods). The samples analyzed were herbal products, foods, soil, and biological samples. Developments also occurred in the areas of quality control, toxicology assessment, and enzyme-inhibitor screening. A table that summarizes the areas, source of natural product, nature of the bioactive analyte, CE conditions, LODs, and corresponding reference is provided. A short description on the theory of CE and insights on future activities of CE on natural products are also presented.

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Section: Methods Developmentmentioning

confidence: 99%

Capillary electrophoresis of natural products: 2011–2012

et al. 2014

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“…FD showed improved sensitivity and selectivity. CE with led‐induced native FD was also used for determination of isoquinoline alkaloids and their cytotoxicity in extracts of Chelidonium majus . In addition, multiplex PCR and fluorescence‐based CE could have been used for identification of deer species from antlers .…”

Section: Detectionmentioning

confidence: 99%

Advance of CE and CEC in phytochemical analysis (2012–2013)

Zhao

Lao

et al. 2013

Electrophoresis

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This article presents an overview of the advance of CE and CEC in phytochemical analysis, based on the literature not mentioned in our previous review papers [Chen, X. J., Zhao, J., Wang, Y. T., Huang, L. Q., Li, S. P., Electrophoresis 2012, 33, 168–179], mainly covering the years 2012–2013. In this article, attention is paid to online preconcentration, rapid separation, and sensitive detection. Selected examples illustrate the applicability of CE and CEC in biomedical, pharmaceutical, environmental, and food analysis. Finally, some general conclusions and future perspectives are given.

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“…These include high performance liquid chromatography (HPLC) combined with mass spectrometry (MS) [1,2] or UV-Vis spectrophotometric detection [3,4] , gas chromatography (GC) [5,6], capillary electrophoresis (CE) [7][8][9], paper-based colorimetric assays [10,11], and infrared [12] and fluorescence spectroscopy [13]. Nowadays, there is an increasing need to exploit methods that are quick, reliable and efficient and, moreover, can be easily automated for on-site analysis.…”

Section: Introductionmentioning

confidence: 99%