Capillary density of skeletal muscle in well-trained and untrained men

Hermansen, Lars; Wachtlová, M

doi:10.1152/jappl.1971.30.6.860

Cited by 141 publications

(68 citation statements)

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“…In a study by Saltin et al (1968) no significant changes in capillary density were observed with inactivity (bed rest) and endurance P. ANDERSEN AND J. HENRIKSSON training. In agreement with this, Hermansen & Wachtlova (1971) found no difference in capillary density between untrained and endurance trained men. However, recent studies have shown both a higher capillary density in trained (compared to untrained) subjects and an increase in capillary density with endurance training (Andersen, 1975;Brodal, Ingjer & Hermansen, 1976).…”

Section: Introductionsupporting

confidence: 82%

Capillary supply of the quadriceps femoris muscle of man: adaptive response to exercise

Andersen¹,

Henriksson²

1977

The Journal of Physiology

658

377

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SUMMARY1. Five subjects trained for 8 weeks on a bicycle ergometer for an average of 40 min/day, four times a week at a work load requiring 80 % of the maximal oxygen uptake (02maX.)-1o2 max. determinations were performed, and muscle biopsies from the quadriceps femoris muscle (vastus lateralis) were taken before, as well as repeatedly during, the training period. The muscle biopsies were histochemically stained for fibre-types (myofibrillar ATPase) and capillaries (amylase-PAS method), and analysed biochemically for succinate dehydrogenase and cytochrome oxidase activities.2. The training programme resulted in a 16% increase in l2max., a 20 % increase in capillary density, a 20 % increase in mean fibre area, and an approximately 40 % increase in the activities of succinate dehydrogenase and cytochrome oxidase.3. The capillary supply to type I, IIA and IIB fibres, expressed as the mean number of capillaries in contact with each fibre-type, relative to fibre-type area, increased equally.4. The present study shows that endurance training constitutes a powerful stimulus for capillary proliferation in human skeletal muscle.

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Section: Introductionsupporting

confidence: 82%

Capillary supply of the quadriceps femoris muscle of man: adaptive response to exercise

Andersen¹,

Henriksson²

1977

The Journal of Physiology

658

377

View full text Add to dashboard Cite

show abstract

“…In contrast, Tp and 50% decay time tended to decrease with increase in inter-probe distance. Since deep tissues that contain muscle have more capillaries than epidermal tissue [10,11], more vasodilator metabolites accumulate and dilate blood vessels during occlusion [12,13]. This is supported by the simultaneous DCS and tissue oxygen saturation measurements performed by Yu et al [9], showing that deeper tissues consume more oxygen than the shallow tissues during cuff occlusion.…”

Section: Discussionmentioning

confidence: 91%

Detection of Blood Flow Speed in Shallow and Deep Tissues Using Diffuse Correlation Spectroscopy

Nakabayashi

Ono

2017

ABE

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Diffuse correlation spectroscopy (DCS) is an emerging optical technique for noninvasive measurement of hemodynamics of living tissues. Using emitter and detector optical probes attached to the body surface, DCS estimates the mean speed of blood ow in the tissue, through which the emitted near-infrared light propagates (blood ow index: BFI). The advantage of DCS is that the mean blood ow in deeper tissues such as muscle layers can be measured noninvasively. To investigate the sensitivity of DCS in detecting the physiological changes of blood ow in deep and shallow tissues, we measured the blood ow speed in 14 healthy participants during a reactive hyperemia test and skin temperature changes. In the reactive hyperemia test, blood ow returned to the steady state faster in deep tissues than in shallow tissues, and temperature-dependent reallocation of local blood ow in shallow and deep tissues was clearly observed. These results demonstrate that DCS can measure the differences in physiological blood ow dynamics in deep and shallow tissues, suggesting the potential use of DCS to noninvasively quantify changes at microcirculation level in both shallow and deep tissue layers.Keywords: diffuse correlation spectroscopy, blood ow speed, reactive hyperemia test, thermoregulatory control of blood ow.Adv Biomed Eng. 6: pp. 53-58, 2017.

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“…The metabolic rate of small species following endurance training should therefore be relatively Body mass (kg) Post-training relative capillary density Figure 6: Relationship between post-endurance-training capillary density, expressed relative to capillary density of untrained individuals, and body mass. Data are from published studies, including a range of training durations, methods, and intensities (Hermansen and Wachtlova 1971;Andersen and Henriksson 1977;Ingjer 1979;Adolfsson et al 1981;Klausen et al 1981;Hoppeler et al 1984Hoppeler et al , 1985Essén-Gustavsson et al 1989;Bigard et al 1991;Rivero et al 1995;McCall et al 1996;Serrano et al 2000;Amaral et al 2001;Waters et al 2004;Chinsomboon et al 2009;Geng et al 2010). …”

Section: Implications For Capillary Densities Cellular Metabolic Ratmentioning

confidence: 99%

Testing Metabolic Theories

Kearney

White

2012

The American Naturalist

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JSTOR is a not-for-profit service that helps scholars, researchers, and students discover, use, and build upon a wide range of content in a trusted digital archive. We use information technology and tools to increase productivity and facilitate new forms of scholarship. For more information about JSTOR, please contact support@jstor.org. abstract: Metabolism is the process by which individual organisms acquire energy and materials from their environment and use them for maintenance, differentiation, growth, and reproduction. There has been a recent push to build an individual-based metabolic underpinning into ecological theory-that is, a metabolic theory of ecology. However, the two main theories of individual metabolism that have been applied in ecology-Kooijman's dynamic energy budget (DEB) theory and the West, Brown, and Enquist (WBE) theoryhave fundamentally different assumptions. Surprisingly, the core assumptions of these two theories have not been rigorously compared from an empirical perspective. Before we can build an understanding of ecology on the basis of individual metabolism, we must resolve the differences between these theories and thus set the appropriate foundation. Here we compare the DEB and WBE theories in detail as applied to ontogenetic growth and metabolic scaling, from which we identify circumstances where their predictions diverge most strongly. Promising experimental areas include manipulative studies of tissue regeneration, body shape, body condition, temperature, and oxygen. Much empirical work designed specifically with DEB and WBE theory in mind is required before any consensus can be reached on the appropriate theoretical basis for a metabolic theory of ecology.

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Capillary density of skeletal muscle in well-trained and untrained men

Cited by 141 publications

References 0 publications

Capillary supply of the quadriceps femoris muscle of man: adaptive response to exercise

Capillary supply of the quadriceps femoris muscle of man: adaptive response to exercise

Detection of Blood Flow Speed in Shallow and Deep Tissues Using Diffuse Correlation Spectroscopy

Testing Metabolic Theories

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