Capillary blood gases in acute exacerbations of COPD

Murphy, Ross; Thethy, Sanjeet; Raby, Simon; Beckley, Jean; Terrace, John D.; Fiddler, Christine; Craig, Michelle; Robertson, Colin E.

doi:10.1016/j.rmedu.2006.03.012

Cited by 3 publications

(2 citation statements)

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“…The correlation between PCO 2 , H + and HCO 3 in arterial and CBGs has been shown to be good and easily reproducible. 8 Cardiomyopathies are not a consistent feature of LGMD but conduction abnormalities may occur. 2,9 Also pulmonary hypertension from restrictive lung disease may lead to right heart failure.…”

Section: Discussionmentioning

confidence: 99%

Anaesthetic management of a woman with autosomal recessive limb-girdle muscular dystrophy for emergency caesarean section

Allen

Maguire

2007

International Journal of Obstetric Anesthesia

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Section: Discussionmentioning

confidence: 99%

Anaesthetic management of a woman with autosomal recessive limb-girdle muscular dystrophy for emergency caesarean section

Allen

Maguire

2007

International Journal of Obstetric Anesthesia

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“…In adult population, capillary BGA is not as disseminated as in child population. Adult BGA acquired from arterialized samples, obtained by warming the skin or applying a vasodilator substance, showed a good agreement with arterial BGA in terms of pH and pCO 2 [18][19][20]. Nevertheless, arterialization is time consuming, preventing its use beyond research purposes.…”

Section: Introductionmentioning

confidence: 98%

Agreement between Arterial and Capillary pH, pCO2, and Lactate in Patients in the Emergency Department

Collot

Malinverni

Haltout

et al. 2021

Emergency Medicine International

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Background. Blood gas analysis (BGA) is a frequent painful procedure in emergency departments. The primary objective of the study was a quantitative analysis to assess the mean difference and 95% confidence interval of the difference between capillary and arterial BGA for pH, pCO2, and lactate. Secondary objective was to measure the sensitivity and specificity of capillary samples to detect altered pH, hypercarbia, and lactic acidosis. Adults admitted to the ED were screened for inclusion. We studied the agreement between the two methods for pH, pCO2, and lactate with Bland-Altman bias plot analysis and receiver operating characteristic curves. Results. One hundred ninety-seven paired analyses were included. Mean difference for pH between arterial and capillary BGA was 0.0095, and 95% limits of agreement (LOA) were −0.048 to 0.067. For pCO2, mean difference was −0.3 mmHg, and 95% LOA were −8.5 to 7.9 mmHg. Lactate mean difference was −0.93 mmol/L, and 95% LOA were −2.7 to 0.8 mmol/L. At a threshold of 7.34, capillary pH had 98% sensitivity and 97% specificity to detect acidemia; at 45.9 mmHg, capillary pCO2 had 89% sensitivity and 96% specificity to detect hypercarbia. At a threshold of 3.5 mmol/L, capillary lactate had 66% sensitivity to detect lactic acidosis. Conclusion. Capillary BGA cannot replace arterial BGA despite high concordance between the two methods for pH and pCO2 and moderate concordance for lactate. Capillary measures had good accuracy when used as a screening tool to detect altered pH and hypercarbia but insufficient sensitivity and specificity when screening for lactic acidosis.

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