Capillarisenol C, a novel bisphenol from Artemisia capillaris, induces autophagic death in hepatocellular carcinoma through endoplasmic reticulum stress
Abstract:In our previous work, we isolated a novel bisphenol named capillarisenol C (Cap C) from Artemisia capillaris. Preliminary studies indicated potential anti-hepatocellular carcinoma (HCC) activity. However, its mechanism remains unclear. In this study, we aimed to investigate the function and molecular mechanism of the anti-HCC activity of Cap C. First, We evaluated the inhibitory effect of Cap C on the viability of HepG2 and Huh7 cells using CCK8 assays. The results showed that Cap C sharply reduced the viabili… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.