Capgras Syndrome and Its Relationship to Neurodegenerative Disease

Josephs, Keith A.

doi:10.1001/archneur.64.12.1762

Cited by 100 publications

(77 citation statements)

References 35 publications

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“…One year later, he developed visual hallucination and parkinsonism at the age of 77. He also presented with Capgras syndrome [16]. At this point, he scored 23 points on MMSE; his neuropsychiatric results are summarized in Table 1.…”

Section: Patientmentioning

confidence: 99%

Early detection of dementia with Lewy bodies in patients with amnestic mild cognitive impairment using 123I-MIBG cardiac scintigraphy

Fujishiro¹,

Nakamura²,

Kitazawa³

et al. 2012

Journal of the Neurological Sciences

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Section: Patientmentioning

confidence: 99%

Early detection of dementia with Lewy bodies in patients with amnestic mild cognitive impairment using 123I-MIBG cardiac scintigraphy

Fujishiro¹,

Nakamura²,

Kitazawa³

et al. 2012

Journal of the Neurological Sciences

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“…Postmortem assessment was not conducted as his family had refused permission for one. An autopsy study conducted by Josephs et al, (2007) on two deceased subjects with CS showed pathological changes consistent with Alzheimer's disease and Lewy bodies dementia. A brain magnetic resonance imaging (MRI) was not also done as his family could not afford to pay for it.…”

Section: Discussionmentioning

confidence: 96%

Capgras syndrome in a very late onset, treatment resistant schizophrenia

Ain

Rosdinom

Raynuha

2015

Int. Psychogeriatr.

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We report a Malay man, with underlying chronic medical illnesses, presenting with positive symptoms of schizophrenia, including Capgras syndrome (CS) at the age of 73. Physical examination and blood investigations were normal and brain CT scan showed age-related cerebral atrophy. Neuropsychological assessment showed probable right hemisphere lesions but relatively intact memory and intellectual functions. Several neuroleptics including depot injections were tried but ineffective. Positive symptoms including CS eventually improved with clozapine before his death from myocardial infarction. This case report highlights the uncommon occurrence of CS in treatment resistant schizophrenia (TRS) of very late onset and its treatment challenges.

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“…36 A case of Capgras syndrome as part of an interictal psychosis was found to be associated with profound hypoperfusion of the right hemisphere. 37 DMS generally and Capgras specifically have also been seen with right-hemisphere temporal and tempoparietal strokes 38,39 and in right-hemisphere traumatic brain injury.…”

Section: Commentary By David a Kahn MDmentioning

confidence: 99%

An Unusual Case of Erotomania and Delusional Misidentification Syndrome

Granstein

Strimbu²,

Francois³

et al. 2015

Journal of Psychiatric Practice

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Delusional misidentification syndromes and erotomania are rare entities, each with several distinct manifestations and no clearly defined treatment regimen. Here we expand upon an earlier literature review and describe the case of a 40-year-old woman with a history of bipolar I disorder who presented after an extended period of medication nonadherence with symptoms consistent with both of these conditions; she believed that the staff on the unit were in fact disguised celebrities and fictional characters, and she claimed to be married to a famous singer. The exact relationship of these symptoms (and indeed, even their basic etiologies) remains unclear; however, both delusional syndromes resolved with a combination of risperidone and lithium therapy. Although earlier literature has suggested pimozide as the most effective agent for treating delusional syndromes, given the more favorable side-effect profile of atypical versus typical antipsychotics, this case suggests a role for risperidone as a first-line treatment in such situations.

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Capgras Syndrome and Its Relationship to Neurodegenerative Disease

Cited by 100 publications

References 35 publications

Early detection of dementia with Lewy bodies in patients with amnestic mild cognitive impairment using 123I-MIBG cardiac scintigraphy

Early detection of dementia with Lewy bodies in patients with amnestic mild cognitive impairment using 123I-MIBG cardiac scintigraphy

Capgras syndrome in a very late onset, treatment resistant schizophrenia

An Unusual Case of Erotomania and Delusional Misidentification Syndrome

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