Cannabis use and acute coronary syndrome

Richards, John R.; Bing, Mary L.; Moulin, Aimee; Elder, Joshua W.; Rominski, Robert T.; Summers, Phillip J.; Laurin, Erik G.

doi:10.1080/15563650.2019.1601735

Cited by 61 publications

(41 citation statements)

References 91 publications

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“…One hypothesis from Stanley and O'Sullivan is that cannabis induces transient coronary vasospasm [66]. This hypothesis is supported by many case reports of patients presenting with MI and normal coronary vessels upon cardiac angiography [67]. Another hypothesis is that the myocardial oxygen supply-demand mismatch causes transient ischemia.…”

Section: Myocardial Infarctionmentioning

confidence: 96%

The Impact of Marijuana on the Cardiovascular System: A Review of the Most Common Cardiovascular Events Associated with Marijuana Use

Latif

Garg

2020

JCM

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With the expanded legalization of marijuana, its medical and recreational use have sharply increased over the past decade. A wide array of new forms of cannabis is available on the market today, and the potencies are ten times those of forms previously tested, meaning that the true impact of marijuana on the cardiovascular system remains unclear. Cannabis mainly exerts its effects via the sympathetic and parasympathetic nervous systems, with different doses affecting different cannabinoids receptors. Studies have shown that marijuana plays a role in thrombosis, inflammation, and atherosclerosis. Case reports have linked marijuana use to myocardial infarction, cardiac arrythmias, cardiomyopathies, stroke, and arteritis. Most patients are young, healthy men with no cardiovascular risk factors; however, the patient population is expected to change to include older individuals in the future. The widespread public perception of safety accompanying marijuana use has contributed to its increased use among the elderly, who are the most at risk population for acute cardiovascular events. In this review, we aim to provide a basic understanding of the physiological effects of marijuana on the cardiovascular system and to review the current literature regarding cardiovascular diseases linked to marijuana use in adults.

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Section: Myocardial Infarctionmentioning

confidence: 96%

The Impact of Marijuana on the Cardiovascular System: A Review of the Most Common Cardiovascular Events Associated with Marijuana Use

Latif

Garg

2020

JCM

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“…The aortic pulsatility during tachycardia could have led to further narrowing of arterial lumen. The patient was also a marijuana smoker which as such is a potential risk factor for acute coronary syndrome [9]. Although the ACAOS was incidentally found, these factors could have propagated the myocardial infarction.…”

Section: Discussionmentioning

confidence: 97%

Anomalous Origins of All Three Coronary Arteries from Separate Ostia within the Right Aortic Cusp: A Case Report and Review of the Literature

Chandrakumar

Patwa

Chowdhury

et al. 2020

AJMCR

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Coronary artery anomalies are congenital defects which are found incidentally or after cardiac events. While these are rare abnormalities with the majority of patients remain asymptomatic and largely undiagnosed, it remains to be a major cause of sudden cardiac death (SCD). Anomalous origin of left coronary artery (ALCA) from the opposite right aortic sinus is extremely rare with less than 100 cases reported to-date. These patients are at increased risk for significant cardiac events, including SCD. In this report, we present a 48-year-old man with hypertension and marijuana use who was admitted initially with multi-lobar pneumonia and acute kidney injury, developed respiratory failure and sustained ST elevation myocardial infarction (STEMI). Coronary angiography demonstrated anomalous origin of all three main coronary arteries arising from right aortic sinus. In this report we also discuss the genesis of this rare and potentially fatal congenital abnormality and we highlight the diagnostic and management strategies available to-date.

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“…Cannabis is associated with an elevated risk for acute coronary syndrome and cardiovascular disease. 28 Long-term cannabis use is linked to increased frequency of anginal events, development of cardiac arrhythmias, peripheral arteritis, coronary vasospasms, and problems with platelet aggregation. 29,30 Strongly caution against cannabis use with patients who have a history of cardiovascular disease, orthostatic hypotension, tachyarrhythmia, or hypertension.…”

Section: Guidelines For Screening and Evaluationmentioning

confidence: 99%

Is your patient’s cannabis use problematic?

Hsü¹

2020

The Journal of Family Practice

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Is your patient's cannabis use problematic? Individuals who do not meet DSM-5 criteria for cannabis use disorder may still have problematic use. The screening tool and 5 interventions detailed here can help. CASE u Jessica F is a new 23-year-old patient at your clinic who is seeing you to discuss her severe anxiety. She also has asthma and reports during your exploration of her family history that her father has been diagnosed with schizophrenia. She has been using 3 cartridges of cannabis vape daily to help "calm her mind" but has never tried other psychotropic medications and has never been referred to a psychiatrist. How would you proceed with this patient?

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Cannabis use and acute coronary syndrome

Cited by 61 publications

References 91 publications

The Impact of Marijuana on the Cardiovascular System: A Review of the Most Common Cardiovascular Events Associated with Marijuana Use

The Impact of Marijuana on the Cardiovascular System: A Review of the Most Common Cardiovascular Events Associated with Marijuana Use

Anomalous Origins of All Three Coronary Arteries from Separate Ostia within the Right Aortic Cusp: A Case Report and Review of the Literature

Is your patient’s cannabis use problematic?

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