Cannabis and Neuropsychiatry, 2: The Longitudinal Risk of Psychosis as an Adverse Outcome

Andrade, Chittaranjan

doi:10.4088/jcp.16f10918

Cited by 17 publications

(9 citation statements)

References 14 publications

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“…The purpose of this study was to determine the consequences of using living kidney donors with a history of marijuana use, and if doing so would compromise either donor or recipient outcomes. Marijuana remains a mind-altering substance that can lead to psychosis, neurodegeneration, poor cognitive development and long-term cognitive deterioration even after a long period of abstinence [40–43]. The cognitive impairment is great enough that driving under the influence of marijuana has been associated with increased traffic accidents and fatalities [42].…”

Section: Discussionmentioning

confidence: 99%

Should donors who have used marijuana be considered candidates for living kidney donation?

Ruckle

Keheila

West

et al. 2018

Clinical Kidney Journal

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Background The use of marijuana in the USA has been steadily increasing over the last 10 years. This study is the first to investigate the effect of marijuana use by live kidney donors upon outcomes in both donors and recipients. Methods Living kidney donor transplants performed between January 2000 and May 2016 in a single academic institution were retrospectively reviewed. Donor and recipient groups were each divided into two groups by donor marijuana usage. Outcomes in donor and recipient groups were compared using t -test, Chi-square and mixed linear analysis (P < 0.05 considered significant). Results This was 294 living renal donor medical records were reviewed including 31 marijuana-using donors (MUD) and 263 non-MUDs (NMUD). It was 230 living kidney recipient records were reviewed including 27 marijuana kidney recipients (MKRs) and 203 non-MKRs (NMKR). There was no difference in donor or recipient perioperative characteristics or postoperative outcomes based upon donor marijuana use (P > 0.05 for all comparisons). There was no difference in renal function between NMUD and MUD groups and no long-term difference in kidney allograft function between NMKR and MKR groups. Conclusions Considering individuals with a history of marijuana use for living kidney donation could increase the donor pool and yield acceptable outcomes.

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Section: Discussionmentioning

confidence: 99%

Should donors who have used marijuana be considered candidates for living kidney donation?

Ruckle

Keheila

West

et al. 2018

Clinical Kidney Journal

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“…In addition, patients with psychotic disorders (van Os et al, 2002 [56]), as well as patients who are genetically predisposed to psychotic disorders, may be more vulnerable to cannabinoid-induced psychotic reactions than patients without psychotic disorders [32,33,34,35]. Previous studies have reported cases in which patients' initial SC-induced psychotic symptoms persisted well beyond their period of intoxication [9,11,34,35,36,37]. …”

Section: Introductionmentioning

confidence: 99%

Synthetic Cannabinoid Use in a Psychiatric Patient Population: A Pilot Study

Welter¹,

Lücke

Lam³

et al. 2017

Eur Addict Res

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Background: Consumption of natural cannabis (NC) and synthetic cannabinoids (SCs) has been associated with psychotic disorders. We compared the prevalence of use, consumer profiles, and psychosis-inducing potential of NC and SCs in a specific high-risk population. Methods: This prospective pilot study included 332 patients (18-64 years, mean 36.83, SD 13.33). Patients' sociodemographics and medical histories as well as illicit substance use and psychiatric symptom histories were collected using a drug consumption survey that assessed the use of new psychoactive substances and the Psychotic Symptoms Interview. Results: In total, 7.2% of all patients, 10.6% of psychotic patients, and 4.5% of nonpsychotic patients reported SC consumption. Compared with SCs, NC was consumed much more frequently by its users (mean 222.73, SD 498.27). NC and SC use induced persistent psychosis. Psychotic symptoms were first experienced by patients with a history of NC or SC use during intoxication and persisted after cessation (>1 year) of drug use. Positive and negative symptoms tended to be more severe in SC and NC users, respectively. Conclusions: NC and SCs may cause different symptom clusters. These relationships should be further evaluated.

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“…Current cannabis abuse or dependence increases the risk of transition into psychosis in persons at ultrahigh risk of psychosis [17, 18]. There have been few studies addressing the effects of caffeine and cannabis in combination, but they have been focused on their combined effects on memory but not in psychosis [19].…”

Section: Discussionmentioning

confidence: 99%

Psychopathology Related to Energy Drinks: A Psychosis Case Report

Hernández-Huerta

Martín-Larrégola

Gómez-Arnau

et al. 2017

Case Reports in Psychiatry

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Energy drinks (ED) are nonalcoholic beverages that have caffeine as their most common active substance. The rapid expansion of ED consumption has created concern in the scientific community as well as in the public opinion. We report a psychotic episode probably triggered by ED abuse in a young adult without previous psychotic disorders. We have reviewed the literature regarding the relationship between caffeine, energy drinks, and psychopathology. Few articles have been published about mental health effects of energy drinks and caffeine abuse. Nevertheless, this relationship has been suggested, specifically with anxiety disorders, manic episodes, suicide attempts, psychotic decompensation, and substance use disorder. ED consumption could represent a global public health problem because of the potential severe adverse effects in mental and physical health. To our knowledge, this article is probably the first case of psychosis related to ED abuse in an individual without previous psychotic disorders.

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Cannabis and Neuropsychiatry, 2: The Longitudinal Risk of Psychosis as an Adverse Outcome

Cited by 17 publications

References 14 publications

Should donors who have used marijuana be considered candidates for living kidney donation?

Should donors who have used marijuana be considered candidates for living kidney donation?

Synthetic Cannabinoid Use in a Psychiatric Patient Population: A Pilot Study

Psychopathology Related to Energy Drinks: A Psychosis Case Report

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