Cannabis and cannabidiol (CBD) for the treatment of fibromyalgia

Berger, Amnon A; Keefe, Joseph; Winnick, Ariel; Gilbert, Elasaf; Eskander, Jonathan P.; Yazdi, Cyrus; Kaye, Alan D.; Viswanath, Omar; Urits, Ivan

doi:10.1016/j.bpa.2020.08.010

Cited by 34 publications

(27 citation statements)

References 85 publications

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“…Opioid-based therapy, whether oral, infusion or transdermal may be effective (23). In trying to avoid opioid use, cannabis has also been gaining recognition in the treatment of chronic pain (24). Infusion therapy may also include options such as ketamine, lidocaine, magnesium, and dexmedetomidine (25)(26)(27)(28)(29)(30), while considering possible side effects, such as toxicity, addiction, and psychosocial harm (31,32).…”

Section: Neck Painmentioning

confidence: 99%

Efficacy of Dry Needling and Acupuncture in the Treatment of Neck Pain

et al. 2021

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Context: Neck pain is a common phenomenon and affects a large segment of the population. Chronic neck pain, lasting more than 3 months, likely occurs in 10% - 30% of patients with acute neck pain and affects up to 288 million cases globally, carrying a significant cost in terms of quality of life, disability, and healthcare dollars. Here we review neck pain background, acupuncture and the evidence that exist to support acupuncture use in chronic neck pain. Results: Neck pain not only affects quality of life directly, but also contributes to depression, job dissatisfaction and reduced productivity. Unfortunately, neck pain is strongly linked to office and computer work and is likely to continue increasing in prevalence. Traditional treatments, such as analgesics, physical therapy, exercise, and non-invasive therapy bring some relief, and invasive therapy is indicated if anatomical pathologies exist. Acupuncture is a form of integrative medicine, originally described and practiced in traditional Chinese medicine and now expanded to include methods including acupressure, dry needling, and others. Traditionally, it focused on restoring the patient’s flow of Qi by puncturing specific points along the meridians. It has previously been shown to be effective in other forms of chronic pain and disability. Clinical trials studying acupuncture for neck pain have shown significant reduction in both pain and associated symptoms. These therapies are reviewed in this text. Conclusions: Neck pain is a common and significant global problem. Acupuncture, dry needling, and cupping were all shown to be effective in alleviating pain both immediately after treatment, as well as provide long-lasting relief. These treatments are generally safe and inexpensive and should be considered as part of a multimodal approach for the treatment of neck pain. More head-to-head studies will provide better data to support a choice of a specific treatment over another.

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Section: Neck Painmentioning

confidence: 99%

Efficacy of Dry Needling and Acupuncture in the Treatment of Neck Pain

et al. 2021

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“…The use of marijuana for IBD symptom relief has also been a topic of recent interest and investigation. Marijuana and cannabis products have been previously studied in other chronic pain conditions ( 34 , 35 ) and conditions of widespread pain ( 25 ). Several studies have suggested that marijuana may reduce abdominal pain in IBD, but these findings would benefit from additional studies and safety information ( 36 ).…”

Section: Evidence Acquisitionmentioning

confidence: 99%

Efficacy of Acupuncture in the Treatment of Chronic Abdominal Pain

Berger¹,

Liu²,

Jin³

et al. 2021

Anesth Pain Med

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Context: Abdominal pain is a widespread complaint and is one of the common reasons leading patients to seek medical care, either in emergency situations or with their primary providers. While acute abdominal pain is a better defined, usually surgical condition, chronic abdominal pain requires longer, typically lifelong, therapy. Chronic abdominal pain may also present with acute flares and complications. Here we review seminal and novel evidence discussing the use of acupuncture in the treatment of abdominal pain, indications, and conditions that may benefit from this approach. Evidence Acquisition: Chronic abdominal pain is a common complaint causing significant morbidity and disability and has a hefty price tag attached. Recent studies show it may be prevalent in as much as 25% of the adult population. It is defined as three episodes of severe abdominal pain over the course of three months. Chronic abdominal pain could be the result of chronicity of acute pain or of chronic pain syndromes, most commonly IBD syndromes and IBS. While a plethora of treatments exists for both conditions, these treatments usually fall short of complete symptom control, and there is a need for complementary measures to curb disability and increase the quality of life in these patients. Acupuncture is a form of integrative medicine that has long been used in Chinese and traditional medicine, based on the rebalancing of the patient’s Qi, or Ying/Yang balance. It has been shown to be effective in treating several other conditions, and novel evidence may expand its use into other fields as well. Clinical trials studying acupuncture in chronic pain conditions have been promising, and recent evidence supports the use of abdominal pain in chronic abdominal pain conditions as well. Though not curative, acupuncture is a complementary approach that helps reduce symptoms and improved quality of life. Conclusions: Chronic abdominal pain is a widespread condition, mostly affected by the IBS and IBD spectrum. Etiologies are still being studied for these conditions, and while novel treatment approaches are absolute game changers for these patients, many continue to experience some level of symptoms and disability. Acupuncture may provide further alleviation of these symptoms in select patients, thus improving quality of life, reducing disability, and saving healthcare dollars. It is a largely safe and inexpensive method that may significantly contribute to the quality of life of selected patients.

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“…27 Recent evidence concerning the use of cannabinoids in fibromyalgia is promising, though it is not without risk, and further research is required to define indications and treatment regimens better. 28 In treatment-resistant fibromyalgia, consultation with physiatry or pain management can appropriately be part of a multidisciplinary approach. Peripheral pain generators are thought to increase central centralization by increasing peripheral input.…”

Section: Current Treatment Options (Most Popular Fda Approved)mentioning

confidence: 99%

Efficacy of acupuncture in the treatment of fibromyalgia

et al. 2021

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Purpose of ReviewFibromyalgia is a highly prevalent chronic pain syndrome that affects up to 4% of the population and causes significant morbidity and disability, with an increasing associated cost. Though many approaches for treatment have been tested, therapy regimens are still elusive, and efficacy is limited. This review summarizes the background of fibromyalgia and acupuncture and reviews the latest and seminal literature discussing the application of acupuncture in fibromyalgia. Recent FindingsFibromyalgia is hard to treat, owing both to its chronicity and poorly understood pathophysiology and etiology. Current treatments target symptoms primarily, and few attempt to address the source. Efficacious treatment requires long-term treatment by a multidisciplinary team. Though several treatments exist, they still fall short with a substantial number of patients. Acupuncture, a form of integrative medicine, has been a part of traditional Chinese medication for generations. Evidence shows that it effectively treats different kinds of pain conditions, including migraines and chronic musculoskeletal pain. Recent studies showed evidence to support its use in fibromyalgia.Clinical trials studying acupuncture in fibromyalgia have shown improvement in pain, quality of sleep, and quality of life, though the quality of evidence is mainly low to medium. Several studies were not able to provide evidence to support real over sham acupuncture. Weighing the overall evidence paints a picture of mixed results between equivocal results to positive. In analyzing these results, one must also consider publication bias supporting the dissemination of positive results.

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Cannabis and cannabidiol (CBD) for the treatment of fibromyalgia

Cited by 34 publications

References 85 publications

Efficacy of Dry Needling and Acupuncture in the Treatment of Neck Pain

Efficacy of Dry Needling and Acupuncture in the Treatment of Neck Pain

Efficacy of Acupuncture in the Treatment of Chronic Abdominal Pain

Efficacy of acupuncture in the treatment of fibromyalgia

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