Cannabis and Alcohol Co-Use and Condomless Anal Sex Among Men Who have Sex with Men Living with HIV: An Event-Level Analysis

Firkey, Madison; Sheinfil, Alan Z.; Ramos, Jeremy; Woolf‐King, Sarah E.

doi:10.1007/s10461-021-03228-6

Cited by 6 publications

(4 citation statements)

References 84 publications

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“…Specifically, the likelihood of participating in unprotected anal intercourse was approximately three times greater during sexual encounters involving both cannabis and alcohol compared with those without any substance consumption. ( Firkey et al, 2021 ). These findings underscore the urgency for additional research aimed at unraveling the underlying mechanisms and designing effective interventions to support individuals grappling with concurrent substance use issues.…”

Section: Discussionmentioning

confidence: 99%

Patterns and Factors Associated With Alcohol Misuse Among Young Black Men Who Have Sex With Men in New York City

Lu,

Vu,

Wilton

et al. 2024

Am J Mens Health

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Alcohol misuse is a significant health concern among gay, bisexual, same-gender-loving, and other men who have sex with men (MSM). Yet, little is known about the severity and predictors of alcohol misuse among self-reported young Black MSM. This study aimed to identify patterns of and factors associated with alcohol misuse in a sample of young Black MSM living in New York City. Baseline data from a randomized controlled trial aimed at improving the uptake of HIV testing among 250 MSM aged 18 to 29 were analyzed. Log-binominal regression analyses were conducted to assess the association of demographic and psychosocial factors with alcohol misuse in the past year and past 3 months among young Black MSM. Overall, 33.2% and 28.0% of young Black MSM in the study experienced alcohol misuse in the past year and past 3 months, respectively. In the adjusted model, factors positively associated with past-year alcohol misuse included marijuana use, a history of drug use, and having one-two or more than two male sex partners. Likewise, participants who used marijuana and those with one-two or more than two male partners were more likely to report past 3-month alcohol misuse. No significant association was found between positive screening for depressive symptoms, chemsex, internalized homophobia, and the likelihood of having alcohol misuse. The high prevalence of alcohol misuse underscores the importance of raising awareness of alcohol misuse and designing alcohol risk reduction programs that jointly address HIV risk among young Black MSM.

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Section: Discussionmentioning

confidence: 99%

Patterns and Factors Associated With Alcohol Misuse Among Young Black Men Who Have Sex With Men in New York City

Lu,

Vu,

Wilton

et al. 2024

Am J Mens Health

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“…Several studies have shown that the relationship between alcohol and sexual behaviors increases the probability of HIV transmission and the absence of use of condoms in anal sexual practice ( 32 – 34 ). Among MSM, the consumption of alcohol is a major determinant of viral infection, such as HIV ( 33 , 35 ).…”

Section: Introductionmentioning

confidence: 99%

“…Some studies have shown that, among MSM, cannabis and alcohol consumption may affect cognitive functions ( 47 , 48 ). This risk is higher than the drug alone, with higher behavioral and social impacts and distress ( 34 ). Similar results have been observed among heterosexual young people, with higher risk of condomless sex ( 49 , 50 ).…”

Section: Introductionmentioning

confidence: 99%

Sexual behaviors, cannabis, alcohol and monkeypox infection

Vallée

2023

Front. Public Health

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The emergence of the monkeypox virus (MPXV) outbreak in 2022 is a worldwide health issue. The rapid increase of monkeypox cases caused the WHO to designate the escalating global monkeypox outbreak a Public Health Emergency of International Concern on July 23, 2022. The WHO has called on the group currently most affected by the virus, men who have sex with men (MSM), to limit their sexual partners. The diminution in number of sexual partners not only decreases the proportion of infected MSM but could also increases the number of days needed to reach a given infection level among the general population. Several behavioral factors could be associated with high levels of different sexual partners, such as cannabis use and alcohol consumption. Firstly, this review focuses on the association between cannabis and alcohol consumption and the number of sexual partners, and their possible impact on the current MPXV outbreak by impairing the immune responses. Secondly, this review investigated in the UK Biobank cohort the relationship between alcohol and cannabis use and the number of sexual partners. Among the 115,604 participants, 1.8% declared to be MSM, 1.9% to be WSW (women having sex with women), 43.3% men heterosexuals and 53.0% women heterosexuals. MSM and WSW showed higher lifetime sexual partners (N = 17.4 (SD:17.52) and N = 13.65 (SD: 13.21), respectively) compared to heterosexual men (N = 6.89 (SD: 9.47) and women (N = 5.19 (SD:6.56), p < 0.001. After adjustment for age, body mass index, lifetime sexual activity, educational and income levels, tobacco and cardiovascular diseases, cannabis use and alcohol consumption remained significantly associated with increase in the number of different sexual partners in all four subgroups. Thus, cannabis use and alcohol consumption may have two detrimental effects on the MPXV outbreak: by participating in the increase of the number of sexual partners which are mainly responsible for the augmentation of the number of new MPXV infected cases and by impairing the immune response to a viral infection. Health and safety policies should address the factors and practices, including chemsex, leading to an increase in risk of sexual behaviors responsible for MPXV dissemination in the worldwide population.

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“…According to the World Health Organization (WHO), 38.4 million people were infected with HIV at the end of 2020, and around 1.5 million people got infected with HIV all over the world in the year 2021. 1,2 Darunavir (DRV, brand name Prezista) has been a Food and Drug Administration (FDA) approved drug since 2006 and is widely used for the treatment of HIV/AIDS patients having drug resistance against various HIV-drugs. [3][4][5][6] DRV is a second-generation protease inhibitor 7 and the principal component of highly active antiretroviral therapy (HAART) regimens for managing acquired immunodeficiency syndrome (AIDS).…”

Section: Introductionmentioning

confidence: 99%

Micro-total process system machine (μ-TPSM) for rapid synthesis of antiretroviral darunavir

et al. 2023

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Cannabis and Alcohol Co-Use and Condomless Anal Sex Among Men Who have Sex with Men Living with HIV: An Event-Level Analysis

Cited by 6 publications

References 84 publications

Patterns and Factors Associated With Alcohol Misuse Among Young Black Men Who Have Sex With Men in New York City

Patterns and Factors Associated With Alcohol Misuse Among Young Black Men Who Have Sex With Men in New York City

Sexual behaviors, cannabis, alcohol and monkeypox infection

Micro-total process system machine (μ-TPSM) for rapid synthesis of antiretroviral darunavir

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