Cannabinoid Hyperemesis Syndrome (CHS)

Marillier, Mathieu; Batisse, Anne; Edel, Yves; Nguyen, An-Hung; Chevallier, Coralie; Pfau, Grégory; Podevin, Philippe; Djezzar, Samira

doi:10.1097/jcp.0000000000000791

Cited by 4 publications

(4 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Our review of the literature identified a total of 25 case series (n = 271) and 105 individual case reports of patients identified with CHS (Table ) . Most of the reported case series and case studies predated the publication of Rome IV criteria for CHS.…”

Section: Resultsmentioning

confidence: 99%

Role of chronic cannabis use: Cyclic vomiting syndrome vs cannabinoid hyperemesis syndrome

Venkatesan

Levinthal

et al. 2019

Neurogastroenterology Motil

View full text Add to dashboard Cite

Cannabis is commonly used in cyclic vomiting syndrome (CVS) due to its antiemetic and anxiolytic properties. Paradoxically, chronic cannabis use in the context of cyclic vomiting has led to the recognition of a putative new disorder called cannabinoid hyperemesis syndrome (CHS). Since its first description in 2004, numerous case series and case reports have emerged describing this phenomenon. Although not pathognomonic, a patient behavior called “compulsive hot water bathing” has been associated with CHS. There is considerable controversy about how CHS is defined. Most of the data remain heterogenous with limited follow‐up, making it difficult to ascertain whether chronic cannabis use is causal, merely a clinical association with CVS, or unmasks or triggers symptoms in patients inherently predisposed to develop CVS. This article will discuss the role of cannabis in the regulation of nausea and vomiting, specifically focusing on both CVS and CHS, in order to address controversies in this context. To this objective, we have collated and analyzed published case series and case reports on CHS in order to determine the number of reported cases that meet current Rome IV criteria for CHS. We have also identified limitations in the existing diagnostic framework and propose revised criteria to diagnose CHS. Future research in this area should improve our understanding of the role of cannabis use in cyclic vomiting and help us better understand and manage this disorder.

show abstract

Section: Resultsmentioning

confidence: 99%

Role of chronic cannabis use: Cyclic vomiting syndrome vs cannabinoid hyperemesis syndrome

Venkatesan

Levinthal

et al. 2019

Neurogastroenterology Motil

View full text Add to dashboard Cite

show abstract

“…Marillier et al (2017) de 19 pacientes, 12 haviam perdido 5 kg ou mais. 6,38 Embora as complicações cardíacas não pareçam comuns nos quadros de SHC, alguns autores verificaram ocorrência de eventos cardíacos associados. Existe descrição de pelo menos um caso de enfarte agudo do miocárdio, por vasoespasmo, em contexto de SHC.…”

Section: Complicaçõesunclassified

Síndrome da Hiperémese dos Canabinoides: Uma Revisão Prática para Clínicos

Ferreira

Oliveira

Dehanov

et al. 2020

View full text Add to dashboard Cite

A primeira descrição clínica da síndrome da hiperémese dos canabinoides advém de um artigo de Allen et al publicado em 2004. Desde então, várias publicações têm-se focado na sua conceptualização e abordagem clínica, embora se mantenha pouco conhecida na comunidade médica. Esta síndrome é caracterizada pela tríade de consumo crónico de canabinoides, hiperémese cíclica, e banhos ou duches quentes compulsivos como forma de alívio sintomatológico. Podem ainda ocorrer dor abdominal e outros sintomas. A sua verdadeira prevalência é desconhecida, embora se acumule evidência de que é mais frequente do que outrora julgado. Foram aventadas várias hipóteses para a sua patogénese, nomeadamente relacionadas com recetores canabinoides e vaniloides, o eixo hipotálamo-hipófise-adrenal e o sistema nervoso simpático. Em termos terapêuticos, justificam-se medidas de suporte (p.e. hidratação) na fase aguda, existindo evidência para a utilização de benzodiazepinas (nomeadamente lorazepam), haloperidol ou capsaicina tópica para alívio sintomático. A única intervenção que interrompe o quadro é a abstinência dos consumos, devendo ser feita psicoeducação e orientação adequadas do doente. O conhecimento relativo a esta patologia encontra-se em crescimento. A falta de sensibilização para a doença pode conduzir a testes de diagnóstico invasivos e dispendiosos, inúmeras idas ao serviço de urgência e manutenção do quadro clínico sem resolução sintomatológica. O presente artigo visa sistematizar as linhas de intervenção clínica e fomentar uma maior consciencialização dos profissionais de saúde sobre esta entidade, permitindo uma melhor identificação e abordagem terapêutica deste quadro.

show abstract

“…What I find most disturbing about the MJ information available to the public is the relative absence of information about its deleterious and sometimes paradoxical effects. Here are two examples that have not received meaningful coverage in the lay press or in Internet news feeds: (1) I have seen three patients successfully treated for panic disorder with cognitiveÀbehavioral therapy (CBT) who had severe panic attacks when they smoked MJ-many advertisements for MJ and other cannabinoids claim that MJ helps with anxiety-the NAS report notes that there is moderate statistical support for MJ to be associated with an increased incidence of social anxiety disorder and limited evidence for a link with increased symptoms of anxiety; and (2) in France, 99 cases of cannabinoid hyperemesis syndrome (CHS) in daily MJ users had been reported 42 -CHS was first reported in Australia 43 and is infrequently reported in the United States-by contrast, the NAS report concludes that there is substantial evidence for the effectiveness of MJ or cannabinoids as anti-nauseates. Despite its anti-nausea effects, women should not use MJ to treat first-trimester nausea (hyperemesis gravidarum) due to the potential for adverse effects on the developing fetal brain.…”

Section: Marijuana and Underreported Risksmentioning

confidence: 99%

Troublesome News, Fake News, Biased or Incomplete News

Shader¹

2018

Clinical Therapeutics

View full text Add to dashboard Cite

Troublesome News, Fake News, Biased or Incomplete News "You can fool all the people some of the time, and some of the people all the time, but you cannot fool all the people all the time."-Attributed to Abraham Lincoln Mary Jo Bang begins her poem about September with these words: "September is work to the center/Of arguments and controversies./Prejudgments and incomprehensions." 1 Although not explicitly about the 9/11 tragedy, this poem, written in 2007, triggered in me thoughts about the incomprehensibility of that horrific event and how many prejudgments, arguments, and controversies about it persist, including conspiracy theories. 2 We often hear variations of the phrase "History repeats itself," or the French quip "The more things change, the more they stay the same." Looking back at some of the events from 2007 supports the veracity of these views 3 : (1) Adam Air Flight 574 disappeared over Indonesia-all passengers were lost at sea; (2) I. Lewis "Scooter" Libby, Chief of Staff for US Vice President Dick Cheney, was convicted on a number of counts of perjury and obstruction of justice, and was pardoned in April 2018 by US President Donald Trump 4 ; (3) the US Department of Justice released an internal audit noting that the FBI had acted illegally when it used the post 9/11 Patriot Act to justify obtaining personal data on American citizens; (4) the US Supreme Court, by a one-vote majority, upheld the ban on partial-birth abortions; (5) major earthquakes occurred off the coasts of Japan and Peru; (6) a gunman using a semi-automatic rifle killed people in a mall in Omaha, Nebraska; (7) former Pakistani Prime Minister Benazir Bhutto was killed by a suicide bomber; and (8) six cruise missiles armed with nuclear warheads were accidently loaded onto a US Air Force bomber and flown over the United States from North Dakota's Minot Air Force base to Louisiana's Barksdale Air Force Base. Troublesome echoes repeat themselves, some identical, others reframed to fit current times and events.

show abstract

Cannabinoid Hyperemesis Syndrome (CHS)

Cited by 4 publications

References 10 publications

Role of chronic cannabis use: Cyclic vomiting syndrome vs cannabinoid hyperemesis syndrome

Role of chronic cannabis use: Cyclic vomiting syndrome vs cannabinoid hyperemesis syndrome

Síndrome da Hiperémese dos Canabinoides: Uma Revisão Prática para Clínicos

Troublesome News, Fake News, Biased or Incomplete News

Contact Info

Product

Resources

About