Canine Parvovirus and Other Canine Enteropathogens

Case report: Long-term survival in puppies assessed with echocardiography, electrocardiography and cardiac troponin I after acute death in littermates due to parvoviral myocarditis

“…Since it is possible for puppies with PMC to not have parvovirus infection in the intestines, the use of point of care CPV-2 testing, in the absence of gastrointestinal clinical signs, may give a negative result but cannot exclude PMC. Infectious risk was considered very low since puppies had repeated negative point of care tests and no clinical signs ( 10 ).…”

“…In puppies, the myocardial cells are rapidly dividing in the 2 weeks just after birth and it is during this time that infection with CPV-2 can result in myocarditis ( 8 ). While reports of myocarditis are rare, parvoviral enteritis remains a significant cause of morbidity and mortality in dogs despite development of an effective vaccine ( 9 , 10 ).…”

Opasnosti za zdravlje - pseći parvovirus i koronavirus u pasa u portugalskim skloništima

“…In shelter settings, rapid and cost-effective screening methods are essential for early detection, isolation, and treatment of infected animals to minimise disease spread (Marques et al, 2023). Point-of-care faecal ELISA antigen testing remains the diagnostic test of choice for CPV in the shelter setting (Doyle, 2021).…”

“…CPV, a member of the Parvoviridae family, was first recognised in 1978 (Zhao et al, 2011) and is characterised by its high stability in the environment, allowing it to persist in contaminated areas for extended periods (Doyle, 2021). This virus primarily targets the rapidly dividing cells of the gastrointestinal tract and bone marrow, leading to clinical signs such as severe gastroenteritis, dehydration, lethargy, and often a high mortality rate if left untreated (Tuteja et al, 2022).…”

“…Less reported is the possibility of puppies infected during the perinatal period developing parvoviral myocarditis (Dines et al, 2023). However, parvoviral enteritis is a considerable cause of morbidity and mortality despite vaccination protocols (Doyle, 2021). CCoV, on the other hand, is a member of the Coronaviridae family and, although it typically causes mild gastrointestinal clinical signs in infected dogs, it can exacerbate signs when co-infecting with CPV or other pathogens (Buonavoglia et al, 2023).…”