Canine model of surgical stress response comparing standard laparoscopic, microlaparoscopic, and hand-assisted laparoscopic nephrectomy

Experimental and Clinical Evaluation of Transperitoneal Laparoscopic Ureteronephrectomy in Dogs

“…Despite this being the first cohort of clinical canine cases treated with TLU, evidence from experimental and human studies may allow us to hypothesize several advantages of a TLU technique over open ureteronephrectomy. In 1 study, a canine model was used to demonstrate a decrease in serum cortisol concentrations, a commonly described marker of surgical stress, in dogs undergoing a laparoscopic approach compared with open ureteronephrectomy . In people, TLU has other advantages over open nephrectomy including reduced blood loss, hospital stay, pain medication requirement, and more rapid return to normal activity .…”

“…The choice of approach in people appears to be largely based on the surgeon's personal preference with few differences in operative time, blood loss, complications, and hospital stay being reported although some surgeons appear to favor a transperitoneal approach for larger renal masses . Human studies have shown that patients undergoing laparoscopic ureteronephrectomy have reduced blood loss, hospital stay, pain medication requirement, and more rapid return to normal activity compared to those undergoing open nephrectomy Several studies document the use of laparoscopic ureteronephrectomy in canine research models and textbook descriptions of the procedure have been published; however, we are unaware of reports of the results of transperitoneal laparoscopic ureteronephrectomy (TLU) performed in clinical canine cases.…”

Intraoperative Changes in Blood Pressure, Heart Rate, Plasma Vasopressin, and Urinary Noradrenalin During Elective Ovariohysterectomy in Dogs: Repeatability at Removal of the 1st and 2nd Ovary

“…Development of new surgical techniques is important; however, evaluation of their efficacy remains a challenge. Surgical procedures cause a stress response, which is used for assessment purposes . Measurements of the intraoperative surgical stress response can indicate which portion of the intraoperative interventions cause most noxious stimuli, and the subsequent postoperative pain as the magnitude of the stress response is proportional to the degree of trauma …”

Effects of Level of Consciousness on Urodynamic Procedure in Female Cats

“…Cortisol is an important hormone in the body that is secreted by adrenal glands. It is frequently used in various experimental settings as an objective marker when evaluating psychological and laboratory stress (12, 13). Although it remains unclear whether systemic stress induced by urodynamic evaluation adversely influences the examination results, it is necessary to reduce examination-induced systemic stress from an ethical point of view.…”