Canine mammary gland tumors

Sørenmo, Karin U.

doi:10.1016/s0195-5616(03)00020-2

Cited by 289 publications

(392 citation statements)

References 70 publications

Supporting

Mentioning

300

Contrasting

Unclassified

Order By: Relevance

“…Both the TNM system classification and staging provide valuable prognostic information that can be used to determine whether tumors can be adequately treated with local therapy or if they require an adjuvant treatment. 16 Acute phase proteins (APPs) are serum proteins whose concentrations change as a part of an innate host defense system called acute phase response. Positive APPs increase in concentration after inflammation and can be divided into major and moderate APPs.…”

Section: Introductionmentioning

confidence: 99%

Serum Acute Phase Protein Concentrations in Female Dogs with Mammary Tumors

et al. 2009

View full text Add to dashboard Cite

Abstract. Acute phase proteins (APPs) are proteins whose concentrations in serum change after any inflammatory stimulus or tissue damage. The aim of the current study was to evaluate 3 positive APPs (Creactive protein, serum amyloid A, and haptoglobin) and 1 negative APP (albumin) in female dogs with mammary neoplasia. Acute phase proteins were studied in 70 female dogs aged 8-12 years in the following groups: healthy (n 5 10); mammary tumors in stages I (n 5 19), II (n 5 5), III (n 5 6), IV (n 5 5), and V (n 5 7); and with mammary neoplasia plus a concomitant disease (n 5 18). In animals with mammary neoplasia, significant increases of positive APPs were only detected in those that had metastasis or a neoplasm with a diameter greater than 5 cm and ulceration. Dogs with mammary neoplasia and a concomitant disease also had high C-reactive protein concentrations. Albumin concentration was decreased in animals with metastasis and with a concomitant disease. The results of the present study indicate that the acute phase response could be stimulated in female dogs with mammary gland tumors because of different factors, such as metastasis, large size of the primary mass, and ulceration or secondary inflammation of the neoplasm.

show abstract

Section: Introductionmentioning

confidence: 99%

Serum Acute Phase Protein Concentrations in Female Dogs with Mammary Tumors

et al. 2009

View full text Add to dashboard Cite

show abstract

“…Clínicamente, el tumor mamario se mostró bien delimitado, de base pedunculada, de aspecto fluctuante, indoloro y de crecimiento no invasivo (figura 1a), características que son propias de una neoplasia de baja malignidad (Sorenmo 2003). El examen clínico general y las pruebas complementarias no revelaron alteraciones que sugieran cambios paraneoplásicos (datos no mostrados), estadificándose la neoplasia en estadio clínico III.…”

Section: Resultados Y Discusiónunclassified

“…En el diagnóstico de la neoplasia mamaria no se recomienda el aspirado con aguja fina para citología debido a que es un método de baja sensibilidad (Sorenmo 2003). No obstante ya que la masa original era quística, se consideró relevante hacer un análisis morfológico del sedimento celular del líquido intratumoral.…”

Section: Resultados Y Discusiónunclassified

“…El estudio histopatológico fue concordante con un carcinoma tubular simple de grado histológico I (figura 2b) según lo descrito por Goldschmidt y col (2011). Al respecto, Sorenmo (2003) y Cassali y col (2011) describen que los carcinomas tubulares de bajo grado histológico, pese a ser de naturaleza histológica maligna, tienen bajo potencial de reaparición local y metástasis, lo que se traduce en una alta probabilidad de tiempos de sobrevida prolongados posterior al manejo quirúrgico.…”

Section: Resultados Y Discusiónunclassified

See 1 more Smart Citation

Carcinoma mamario en un canino macho: caracterización clínica e inmunohistoquímica

2015

View full text Add to dashboard Cite

“…Histologically, approximately 41%-53% of mammary tumours in bitches are diagnosed as malignant (17). The incidence of mammary carcinomas in dogs is three times higher than in humans (15,26). Histopatological and clinical aspects of canine mammary tumours have been widely reviewed; nevertheless, the presence of considerable variations in the biological behaviour, even among histologically malignant tumours, often does not allow an accurate prognosis using microscopic examination alone (9).…”

Section: Introductionmentioning

confidence: 99%

Immunohistochemical detection of tumour cell proliferation and intratumoural microvessel density in canine malignant mammary tumours

Şennazlı

Yıldırım

Arun

et al. 2015

Bulletin of the Veterinary Institute in Pulawy

View full text Add to dashboard Cite

The objective of this study was to investigate the correlation between different histological types and grades of canine malignant mammary tumours, tumour cell proliferation and their angiogenic activity using immunohistochemical markers. Mammary tissue samples from 47 bitches with mammary cancer were evaluated. The expression of cellular proliferation marker Ki-67 and endothelial marker Von Willebrand's factor (vWF) were immunohistochemically demonstrated. The tumours with the highest Ki-67 and vWF expressions were found to share similar histomorphological features. Simple solid carcinoma had the highest levels of Ki-67, vWF, and higher histological grade while complex carcinomas, osteosarcomas, and carcinosarcomas had the lowest ones. The differences between the expressions of Ki-67 and vWF in different tumour types were considered to be of great importance in determination of biological behaviour and prognosis of these tumours. This study is one of the few studies that evaluate these differences among the subtypes of malignant canine mammary tumours.

show abstract

Canine mammary gland tumors

Cited by 289 publications

References 70 publications

Serum Acute Phase Protein Concentrations in Female Dogs with Mammary Tumors

Serum Acute Phase Protein Concentrations in Female Dogs with Mammary Tumors

Carcinoma mamario en un canino macho: caracterización clínica e inmunohistoquímica

Immunohistochemical detection of tumour cell proliferation and intratumoural microvessel density in canine malignant mammary tumours

Contact Info

Product

Resources

About