Background: Appropriateness use criteria (2011) were developed to guide the rational ordering of a cardiac imaging including transthoracic echocardiography (TTE), as a means of optimizing clinical outcomes while preventing unwarranted costs to the healthcare system. We aimed to evaluate concordance of TTE referrals against published appropriateness criteria.Methods: This was a retrospective audit of consecutive patients admitted to General Medicine, The Alfred Hospital from 1/1/2014 to 25/3/2014. Clinical and TTE characteristics were extracted by manual chart review.Results: Inpatient TTE referrals were made in 109 of 704 (15.5%) admissions in 107 patients. Patient characteristics included male gender in 63%, mean age 75 years (range 28 to 97 years) and 98 (92%) were home dwellers with 5 (4.7%) from residential aged care. Prevalence of co-morbidities included hypertension (60%), ischaemic heart disease (44%), heart failure (40%), atrial fibrillation (33%), diabetes (33%), chronic kidney disease (23%), chronic obstructive airways disease (21%), active malignancy (18%) and dementia (4.7%). TTE had been performed in the previous 12 months in 21% (23/109) of referrals. Of 109 referrals, 90 (83%) were appropriate, 10 (9.2%) uncertain and 9 (8.3%) were inappropriate. The most common inappropriate indication was evaluation of a murmur with no other signs or symptoms related to valvular or structural heart disease. TTE results were available in the discharge summary in 71 (65%) of admissions but where not documented (n = 38), no follow up of results was arranged in 28 (74%). Performance of TTE from request occurred within 2 days in 76.1%, 3 to 4 days in 17.4 %, 5-7 days in 5.5 % and >7 days in 0.9%.
Conclusions:This audit revealed that nearly 1 in 10 TTE referrals were inappropriate and could have been avoided.Furthermore, over one third of TTE results were not documented in discharge summaries with followup not arranged in the majority of these patients. Strategies to reduce inappropriate TTE investigations and systems to address follow up of results are opportunities for further improvement. . This risk-averse tendency with fear of bleeding may be responsible for underdosing with warfarin ("low-intensity anticoagulation") despite a proven lack of efficacy without improved safety [2]. Akin to the warfarin data, emerging registry evidence from non-Vitamin K antagonist (VKA) anticoagulants (NOACs) including dabigatran [3] and rivaroxaban [4] suggests that widespread underdosing of NOACs is commonplace. Whether this occurs in Australian practice is unknown.
UNDERDOSING OF NOACS FOR AF: OLD HABITS DIE HARDObjectives: This study was the first in Australia to specifically identify the proportion of underdosed "real-world" patients treated with a NOAC (either apixaban or rivaroxaban) in our tertiary centre.Methods: All new prescriptions of reduced dose apixaban and rivaroxaban were analysed from centralized electronic pharmaceutical records between 01/04/2014 and 31/03/2015. Based on the strict criteria for dose reduction in...