Candidemia: Candida parapsilosis en una unidad de Neonatología

Durán, Estrella Montolío; Ocáriz, Inmaculada Ramírez de; Ventura, Purificación; Gil, José J.; Rubio, Carmen

doi:10.1016/s1130-1406(05)70012-7

Cited by 6 publications

(4 citation statements)

References 6 publications

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“…The demographic and clinical characteristics of neonates with candidemia in the present study paralleled previous studies in some respects: prematurity, use of central venous catheterization, use of prolonged antibiotic treatment, prolonged mechanical ventilation, prolonged parenteral nutrition, and prolonged hospitalization 29,30 . Eighty‐six of the present cases involved premature infants, and all of the present patients had received previous antibiotic treatment in different combinations of cefotaxime, amikacin, vancomycin and carbapenem.…”

Section: Discussionsupporting

confidence: 79%

Neonatal candidiasis: Results of an 8 year study

Çelebi

Hacımustafaoğlu

Köksal³

et al. 2012

Pediatrics International

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Section: Discussionsupporting

confidence: 79%

Neonatal candidiasis: Results of an 8 year study

Çelebi

Hacımustafaoğlu

Köksal³

et al. 2012

Pediatrics International

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“…Our patients had met the known risk factors for candidemia, such as prematurity, VLWB, use of central venous lines, intubation, parenteral nutrition, and prolonged hospitalization [7,8].…”

Section: Discussionmentioning

confidence: 99%

Outbreak of Candida parapsilosis in a neonatal intensive care unit: a health care workers source

et al. 2009

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Nosocomial neonatal candidiasis is a major problem in infants, which require intensive therapy. The subjects of the present study were three preterm infants admitted to the neonatal intensive care unit of the General Hospital "Dr. Manuel Gea Gonzalez". The infants developed Candida parapsilosis infection on the mean age of 13.6 day of life. Prior to fungemia, infants had received assisted ventilation and hyperalimentation through central venous catheter. Sequence analysis of the internal transcribed spacer gene ruled out other Candida species and revealed that the eight isolates were C. parapsilosis. The isolates were examined based on their molecular relation by random amplified polymorphic DNA analysis. The profiles allowed the identification of two main genotypes of C. parapsilosis as the outbreak cause and as a result of the cross-infection with health care workers' hands. We conclude that C. parapsilosis commonly colonize through horizontal transmission due to the staff's noncompliance of hand hygiene procedures.

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“…The increased use of invasive medical procedures as well as the prophylactic and empirical use of antifungal drugs, especially those of azolic derivation, has been blamed for the emergence of the non-albicans species of Candida (10,12,19).…”

mentioning

confidence: 99%

“…The yeast is capable of forming biofilm in gucosilated solutions and adhering to plastic materials, such as catheters used for parenteral nutrition. Over the last few years, outbreaks and clusters of cross-transmission, total parenteral nutrition solutions, intravascular devices, and medications have been related to C. parapsilosis fungemia (5,10,21). In addition, C. parapsilosis is an important pathogen of onychomycosis in fingernails (3,11).…”

mentioning

confidence: 99%

Candida isolates in tertiary hospitals in northeastern Brazil

Hinrichsen

Falcão²,

Vilella

et al. 2009

Braz. J. Microbiol.

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Candida is an opportunistic pathogen that affects high-risk patients who are either immunocompromised or critically ill and is associated with almost 80% of all nosocomial fungal infections, representing the major cause of fungemia with high mortality rates (40%). Candida albicans is the main cause of candidemia and among the non-albicans species C. parapsilosis, C. glabrata and C. tropicalis are the most frequent agents.

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Candidemia: Candida parapsilosis en una unidad de Neonatología

Cited by 6 publications

References 6 publications

Neonatal candidiasis: Results of an 8 year study

Neonatal candidiasis: Results of an 8 year study

Outbreak of Candida parapsilosis in a neonatal intensive care unit: a health care workers source

Candida isolates in tertiary hospitals in northeastern Brazil

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