Candida species contamination in drinking groundwater from residence wells in three municipalities of midwestern Brazil and the potential human health risks

Cupozak-Pinheiro, Wellinton Jhon; Almeida-Apolonio, Adriana Araújo de; Sasaki, Melina Hatsue; Maran, Nayara Halimy; Araújo, Renata Pires de; Silva, Danielly Beraldo dos Santos; Santos, João Víctor de Andrade dos; Barufatti, Alexéia; Chang, Marilene Rodrigues; Oliveira, Kelly Mari Pires de

doi:10.1016/j.micpath.2022.105660

Cited by 4 publications

(3 citation statements)

References 52 publications

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“…Indeed, tests using amphotericin B, itraconazole, fluconazole, econazole, ketoconazole, and micafungin are commonly reported in the literature [75][76][77][78]. Some works have informed the study of fungal species present in aquatic systems and their susceptibility to distinct groups of antifungal agents [42,[79][80][81]. For instance, Milanezi et al tested 104 samples and found that 95 yeast isolates and 63 were resistant to at least one antifungal of the azole class.…”

Section: Susceptibility Resistance To Antifungals and Resistant Fungi...mentioning

confidence: 99%

Alternative and Classical Processes for Disinfection of Water Polluted by Fungi: A Systematic Review

Caicedo-Bejarano,

Morante-Caicedo,

Castro-Narváez

et al. 2024

Water

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The introduction of the first list of priority pathogenic fungi by the World Health Organization stresses the need to research and develop public health actions to mitigate infections caused by fungi. One of those actions involves the water disinfection systems, which comprise classical and alternative methods that have been developed in the last decades. Thereby, this work reviews the disinfection of fungi by classical methods such as chlorination, ozonation, and ultraviolet (UV) treatments and alternative advanced oxidation processes (AOPs) such as photo-Fenton, photocatalysis, or couplings of UV with peroxides. The matrices of aquatic systems (sewage, groundwater, drinking water, among others) were considered. A bibliometric analysis is performed initially, and then some aspects of the resistance to antifungals are presented, and the efficiency of the diverse processes in the reduction in fungal loading is also revised. Herein, it is shown the role of the disinfecting agents (e.g., chlorine, hydroxyl radical, or light) and their effects on fungi structures (e.g., direct DNA damage, or indirect damage due to the action of radicals). Moreover, gaps, such as the treatment of antifungal-resistant fungi and limited information about combinations among AOPs, related to the disinfection of water polluted by fungi, were identified.

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Section: Susceptibility Resistance To Antifungals and Resistant Fungi...mentioning

confidence: 99%

Alternative and Classical Processes for Disinfection of Water Polluted by Fungi: A Systematic Review

Caicedo-Bejarano,

Morante-Caicedo,

Castro-Narváez

et al. 2024

Water

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“…Yeasts of the genus Candida can be isolated from samples of groundwater, mineral water, domestic and industrial wastewater, rivers, and lakes, demonstrating the ubiquity of this genus and its ability to adapt to different environments. Candida species cause opportunistic infections in both healthy and immunocompromised individuals, including candidiasis, candiduria, and nail mycosis, as well as systemic infections that can debilitate patients or even lead to death [158]. Approximately 75% of all Candida infections in humans are caused by C. albicans, while C. glabrata, C. parapsilosis, and C. tropicalis are important emerging pathogens related to nosocomial infections.…”

Section: Fungi and Fungus-like Microorganisms (Oomycetes)mentioning

confidence: 99%

“…Approximately 75% of all Candida infections in humans are caused by C. albicans, while C. glabrata, C. parapsilosis, and C. tropicalis are important emerging pathogens related to nosocomial infections. It is reported that C. albicans causes > 150 million mucosal infections and ~200,000 deaths per annum due to invasive and disseminated disease in susceptible individuals [158,159]. Furthermore, C. albicans is a cause of mycotic infections with economic importance in freshwater Nile tilapia (Oreochromis niloticus), common carp (Cyprinus carpio), catfish (Clarias gariepinus), and grey mullet (Mugil cephalus) [103,160].…”

Section: Fungi and Fungus-like Microorganisms (Oomycetes)mentioning

confidence: 99%

Microbial Pathogens in Aquaponics Potentially Hazardous for Human Health

Dinev,

Velichkova,

Stoyanova

et al. 2023

Microorganisms

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The union of aquaculture and hydroponics is named aquaponics—a system where microorganisms, fish and plants coexist in a water environment. Bacteria are essential in processes which are fundamental for the functioning and equilibrium of aquaponic systems. Such processes are nitrification, extraction of various macro- and micronutrients from the feed leftovers and feces, etc. However, in aquaponics there are not only beneficial, but also potentially hazardous microorganisms of fish, human, and plant origin. It is important to establish the presence of human pathogens, their way of entering the aforementioned systems, and their control in order to assess the risk to human health when consuming plants and fish grown in aquaponics. Literature analysis shows that aquaponic bacteria and yeasts are mainly pathogenic to fish and humans but rarely to plants, while most of the molds are pathogenic to humans, plants, and fish. Since the various human pathogenic bacteria and fungi found in aquaponics enter the water when proper hygiene practices are not applied and followed, if these requirements are met, aquaponic systems are a good choice for growing healthy fish and plants safe for human consumption. However, many of the aquaponic pathogens are listed in the WHO list of drug-resistant bacteria for which new antibiotics are urgently needed, making disease control by antibiotics a real challenge. Because pathogen control by conventional physical methods, chemical methods, and antibiotic treatment is potentially harmful to humans, fish, plants, and beneficial microorganisms, a biological control with antagonistic microorganisms, phytotherapy, bacteriophage therapy, and nanomedicine are potential alternatives to these methods.

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Chemical composition and biological activities of the infusion of leaves of Campomanesia guazumifolia (Cambess.) O.Berg: Tea with nutraceutical and medicinal potential

et al. 2023

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Candida species contamination in drinking groundwater from residence wells in three municipalities of midwestern Brazil and the potential human health risks

Cited by 4 publications

References 52 publications

Alternative and Classical Processes for Disinfection of Water Polluted by Fungi: A Systematic Review

Alternative and Classical Processes for Disinfection of Water Polluted by Fungi: A Systematic Review

Microbial Pathogens in Aquaponics Potentially Hazardous for Human Health

Chemical composition and biological activities of the infusion of leaves of Campomanesia guazumifolia (Cambess.) O.Berg: Tea with nutraceutical and medicinal potential

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