Candida parapsilosis prosthetic valve endocarditis

Abstract

Candida endocarditis is a rare infection associated with high mortality and morbidity. There are still some controversies about Candida endocarditis treatment, especially about the treatment duration. We report a case of a Candida parapsilosis endocarditis that presented as a lower limb ischemia. The patient was surgically treated with a cryopreserved homograft aortic replacement. We used intravenous fluconazole 800 mg as initial treatment, followed with 12 months of 400 mg fluconazole per os. The patient outcome was good.

A case series of medically managed Candida parapsilosis complex prosthetic valve endocarditis

“…The outcomes of case 1 and case 2 were successful medical therapy while the conditions of case 3 and case 4 deteriorated, making it important to diagnose Candida parapsilosis complex PVE as early as possible. Besides, in the previous reports, the case in Tan’s report was admitted one month after initial symptoms and the case in Silva-Pinto’s report was admitted ten days after initial symptoms [ 21 , 24 ]. These cases all had a successful medical therapy.…”

Relapsing Candida parapsilosis Endocarditis With Septic Embolization: A Case Report

“…Rare cases of successful treatments with medical therapy alone have been described [19]. Due to lack of randomized studies, there is no consensus on the optimal medical treatment nor its duration [7,20].…”

A case series of medically managed Candida Parapsilosis complex prosthetic valve endocarditis and literature review

“…Through up-to-date review of all previous cases, 12 cases of Candida Parapsilosis complex prosthetic valve endocarditis had been reported (Table 2) [13][14][15][16][17][18][19][20][21][22][23] . Besides, two articles described outbreaks of Candida parapsilosis prosthetic valve endocarditis following cardiac surgery, including 8 dead cases and one alive case without detailed information 24,25 .…”