Candida massiliensis sp. nov. Isolated from a Clinical Sample

Kabtani, Jihane; Boulanouar, Fatima; Militello, Muriel; Cassagne, Carole; Ranque, Stéphane

doi:10.1007/s11046-023-00792-4

Cited by 1 publication

(1 citation statement)

References 28 publications

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“…Environmental and human-induced factors are greatly impacting the evolution, selection, and adaptation of previously harmless fungal species, which are now posing a growing threat to the health of humans and animals [ 32 ]. This is the case for Candida viswanathii , C. auris , C. blankii , C. palmioleophila , C. vulturna , C. massiliensis , Trichophyton indotineae , Pseudogymnoascus destructans , Batrachochytrium dendrobatidis , and Kodamaea ohmeri , all of which are environmental fungi that have been successfully adapted to animals or humans over time [ 12 , 18 , 31 , 33 , 34 , 35 , 36 ].…”

Section: Discussionmentioning

confidence: 99%

First Report of the Emerging Pathogen Kodamaea ohmeri in Honduras

Ortiz,

López,

Muñoz

et al. 2024

JoF

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Kodamaea ohmeri is an environmental yeast considered a rare emerging pathogen. In clinical settings, the correct identification of this yeast is relevant because some isolates are associated with resistance to antifungals. There is a lack of available data regarding the geographical distribution, virulence, and drug resistance profile of K. ohmeri. To contribute to the knowledge of this yeast, this study aimed to describe in depth three isolates of K. ohmeri associated with fungemia in Honduras. The identification of the isolates was carried out by sequencing the ribosomal ITS region. In addition, the susceptibility profile to antifungals was determined, and some properties associated with virulence were evaluated (exoenzyme production, biofilm formation, cell adhesion, and invasion). The isolates showed strong protease, phospholipase, and hemolysin activity, in addition to being biofilm producers. Adherence and invasion capacity were evident in the HeLa and Raw 264.7 cell lines, respectively. This study expands the understanding of the underlying biological traits associated with virulence in K. ohmeri, and it is the first report of the detection and identification of K. ohmeri in Honduras as a cause of human infection.

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