Candida Infection of the Gastrointestinal Tract

Eras, Philip; Goldstein, Michael J.; Sherlock, Paul

doi:10.1097/00005792-197209000-00002

Cited by 258 publications

(100 citation statements)

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“…1,4,7,8 The discrepancy between these data would appear to be due to the criteria used to diagnose fungal colonization, the age of the patients studied, concurrent disease, and the pharmacotherapy applied. Assessment of the factors that might enhance fungal infection, in patients with gastric ulcer disease, revealed that fungal infection was associated with increased age.…”

Section: Discussionmentioning

confidence: 99%

Treatment of Gastric Candidiasis in Patients with Gastric Ulcer Disease: Are Antifungal Agents Necessary?

Jung

Jeon²,

Cho³

et al. 2009

Gut Liver

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Background/Aims: The inadequacy of information on the treatment of gastric candidiasis with antifungal agents promoted us to evaluate patients with fungal infections who had gastric ulcers and assess the need for proton-pump inhibitors or antifungal agents. Methods: Sixteen patients were included in the study. The criterion for the diagnosis of candidiasis was finding yeast and hyphae in the tissue or an ulcer on histological sections of biopsy samples. Surface fungi were not considered infections. Results: In all cases with benign ulcers, follow-up endoscopy performed 6 weeks after proton-pump-inhibitor treatment revealed that the ulcer had improved without antifungal medication. However, in patients with malignant ulcers, surgical resection was necessary for a definitive cure. Two patients with lymphoma received combined chemotherapy and a proton-pump inhibitor, which improved their condition. Conclusions: The results of this study suggest that benign ulcers with candidiasis can be effectively treated by a proton-pump inhibitor without antifungal medication. However, surgical resection should be considered for malignant ulcers with candidiasis. (Gut and Liver 2009;3:31-34)

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Section: Discussionmentioning

confidence: 99%

Treatment of Gastric Candidiasis in Patients with Gastric Ulcer Disease: Are Antifungal Agents Necessary?

Jung

Jeon²,

Cho³

et al. 2009

Gut Liver

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“…In both instances, Candida cells formed, or were part of, microcolonies in the mucosa. If such microcolonies are formed in man it may explain, in part, why isolated plaques are often seen on examination of intestinal mucosa infected with C. albicans (Eras et al, 1972;Joshi et al, 1981). It has been suggested that microcolony formation is of ecological and pathological importance in the colonisation of mucosal surfaces by other micro-organisms Costerton et al, 1981Costerton et al, , 1985.…”

Section: Discussionmentioning

confidence: 99%

Mechanisms of association of Candida albicans with intestinal mucosa

Kennedy

Volz

Edwards

et al. 1987

Journal of Medical Microbiology

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“…In one study which was done by Ears et al, gut mycosis was observed in 109(4.35%) of the 2517 total cases which were studied from 1960-1964 [7]. In Japan, Tsukamoto et al, reported that gut mycosis was present in 196(5.9%) of the 3,339 cases which were reported from 1971 to 1983 [8].…”

Section: Pathology Section Nalini Guptamentioning

confidence: 99%

“…In Japan, Tsukamoto et al, reported that gut mycosis was present in 196(5.9%) of the 3,339 cases which were reported from 1971 to 1983 [8]. In these reports, the most commonly effected organ was the oesophagus, followed by the stomach, the small intestine and the large intestine [7,8]. Minali et al, reported that stomach candidiasis was seen in 0.96% of the upper intestinal endoscopies [9].…”

Section: Pathology Section Nalini Guptamentioning

confidence: 99%

A Rare Cause of Gastric Perforation-Candida Infection: A Case Report and Review of the Literature

Gupta¹

2012

JCDR

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Fungal microorganisms as a cause of gastric perforation, is very rare. Most of the cases of gastric perforation are seen as the complications of peptic ulcer disease, the intake of NSAIDs (Non Steroidal Anti-Inflammatory Drugs), neoplastic diseases, etc. We are reporting a case of a 50 year old male who presented with a sudden onset of abdominal pain and shock and was diagnosed as acute peritonitis which was caused by a gastrointestinal perforation. An emergency exploratory laporotomy was performed and a gastric perforation repair with omentoplexy was done. However, the patient died in the post operative period due to a sudden cardiac arrest. A gastric perforation edge biopsy revealed the presence of fungal hyphae. The peritoneal fluid culture revealed Candida albicans colonies.

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Candida Infection of the Gastrointestinal Tract

Cited by 258 publications

References 0 publications

Treatment of Gastric Candidiasis in Patients with Gastric Ulcer Disease: Are Antifungal Agents Necessary?

Treatment of Gastric Candidiasis in Patients with Gastric Ulcer Disease: Are Antifungal Agents Necessary?

Mechanisms of association of Candida albicans with intestinal mucosa

A Rare Cause of Gastric Perforation-Candida Infection: A Case Report and Review of the Literature

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