Candida-Associated Denture Stomatitis: Clinical Relevant Aspects

Vasconcellos, Andréa Araújo de; Gonçalves, Letícia Machado; Cury, Altair Antoninha Del Bel; Silva, Wander José da

doi:10.1007/978-3-662-47194-4_7

Cited by 8 publications

(7 citation statements)

References 27 publications

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“…The case reported comes under type II of this classification. It was chronic infection caused by the microbial agents associated with mechanical injury due to wearing denture constantly day and night, along with poor oral hygiene 4 . In order to prevent this condition maintenance of a good oral hygiene is pivotal.…”

Section: Discussionmentioning

confidence: 99%

“…It is a known factor that Candida albicans is the major cause of this condition. Maxilla is the most common site of his condition because fungal growth is aggravated by Candidal adhesion to maxillary denture fitting surface 3,4 .…”

Section: Introductionmentioning

confidence: 99%

“…According to various studies, incidence of denture stomatitis was more common in women and old age patients. Epidemiologic studies report that candida is the main causative agent of denture induced stomatitis, 60%-70% dentures are found to have fungal hyphae 4 .…”

Section: Introductionmentioning

confidence: 99%

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Denture Induced Stomatitis-A Case Report

Inayat¹,

Hassan²,

Aziz³

et al. 2019

Int. j. endorsing health sci. res.

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Background: Denture hygiene habits are liable to change from one person to another. There has been a close relationship between irregular denture surfaces, poor oral hygiene or ill-fitted denture and opportunistic oral microorganism which leads to diseases like denture induced stomatitis.Case Presentation: A 70-year-old patient reported to the Department of Prosthodontics with a chief complaint of broken denture and pain in oral mucosa. The patient history, oral and denture examination indicated that the patient had denture stomatitis.Management & Results: The patient was advised to have good oral hygiene and anti-microbial gels. After a week of follow up, the patient showed good results with the treatment. Conclusion:It can be concluded that the patient needs to be educated regarding denture and oral hygiene is the most important step to prevent this type of disease.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Denture Induced Stomatitis-A Case Report

Inayat¹,

Hassan²,

Aziz³

et al. 2019

Int. j. endorsing health sci. res.

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“…One in every three denture wearers suffers from DS, the most common oral mucosal lesion associated with removable dentures [ 28 ]. The prevalence of DS ranges from 60 to 70% in denture wearers who exhibit clinical signs and symptoms [ 18 , 21 ]; however, this percentage may be up to 75% if asymptomatic patients are included [ 33 ].…”

Section: Introductionmentioning

confidence: 99%

Management of Chronic Atrophic Candidiasis (Denture Stomatitis)—A Narrative Review

Abuhajar

Ali

Zulfiqar

et al. 2023

IJERPH

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One of the most common oral diseases affecting people wearing dentures is chronic atrophic candidiasis or denture stomatitis (DS). The aim of the paper is to provide an update on the pathogenesis, presentation, and management of DS in general dental practice settings. A comprehensive review of the literature published in the last ten years was undertaken using multiple databases, including PubMed via MEDLINE, EMBASE, and Scopus. The eligible articles were analyzed to identify evidence-based strategies for the management of DS. Despite its multifactorial nature, the leading cause of DS is the development of oral Candida albicans biofilm, which is facilitated by poor oral and denture hygiene, long-term denture wear, ill-fitting dentures, and the porosity of the acrylic resin in the dentures. DS affects between 17 and 75% of the population wearing dentures, with a slight predominance in elderly females. The mucosal denture surfaces and posterior tongue are the common sites of DS, and the affected areas exhibit erythema, the swelling of the palatal mucosa and edema. Oral and denture hygiene protocols, adjusting or re-fabricating poorly adapting dentures, smoking cessation, avoiding nocturnal denture wear, and the administration of topical or systemic antifungals are the mainstay of management. Alternate treatments such as microwave disinfection, phytomedicine, photodynamic therapy, and incorporation of antifungals and nanoparticles into denture resins are being evaluated for the treatment of DS but require further evidence before routine use in clinical practice. In summary, DS is the most common oral inflammatory lesion experienced by denture wearers. Most patients with DS can be managed in general dental practice settings. Effective management by general dental practitioners may be supported by a thorough understanding of the pathogenesis, the recognition of the clinical presentation, and an awareness of contemporary treatment strategies.

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“…Strategies include antifungal therapy, disinfectants and cleansers, oral hygiene instructions, placement of resilient liner/tissue conditioner, laser treatment, microwave disinfection, and a combination of 2 or more of these. Topical antifungal agents (miconazole 2% and nystatin) or systemic antifungal agents such as fluconazole (FLZ) and ketoconazole 9 have become common treatments, depending on the condition’s severity. Although successful in clinical use, antifungal agent therapy has disadvantages, including side-effects, antimicrobial resistance, 10 and high cost to the patient.…”

Section: Introductionmentioning

confidence: 99%

Effects of trimethylsilane plasma coating on the hydrophobicity of denture base resin and adhesion of Candida albicans on resin surfaces

Liu

Hong

et al. 2017

The Journal of Prosthetic Dentistry

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Statement of problem Candida-associated denture stomatitis (CADS) is the most common oral mucosal lesion among denture wearers. TMS plasma coating may inhibit the growth of Candida albicans (C. albicans) on denture surfaces. Purpose The purpose of this in vitro study was to investigate whether trimethylsilane (TMS) plasma coatings can effectively reduce C. albicans adhesion on denture base acrylic resin surfaces. Material and methods Sixty denture base acrylic resin disks (Lucitone 199) with smooth and rough surface were prepared and were either left untreated (control group) or coated with TMS monomer (experimental group) by using plasma. Contact angles were measured immediately after TMS plasma coating. The morphology of C. albicans adhesion was observed with scanning electron microscopy (SEM). Energy-dispersive spectroscopy (EDS) was used to characterize the elemental composition of the specimen surface. An adhesion test was performed by incubating the resin disk specimens in C. albicans suspensions (1×107 cell/mL) at 37°C for 24 hours and further measuring the optical density (OD) of the C. albicans using a 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) assay kit. One-way ANOVA and 2-way ANOVA were followed by a post hoc test analysis (α=.05). Results The group with TMS coating exhibited a more hydrophobic surface than the control group. EDS analysis revealed successful TMS plasma coating. The difference in the mean contact angles between the uncoated group and the TMS coated group was statistically significant (P<.05), 79.0 ±2.9 degrees versus 105.7 ±1.5 degrees for the smooth surface and 90.2 ±7.6 degrees versus 131.5 ±2.1 degrees for the rough surface. In SEM analysis, the C. albicans biofilm was found to grow more on the surface of the denture base resin without the TMS coating than on the surfaces of the experimental group. In the adhesion test, the amount of C. albicans adhering to the surface of denture base resin with the TMS coating was significantly less than that on the surfaces without TMS coating (P<.05). Conclusions TMS coating significantly reduced the adhesion of C. albicans to the denture base resin and might reduce denture stomatitis.

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Candida-Associated Denture Stomatitis: Clinical Relevant Aspects

Cited by 8 publications

References 27 publications

Denture Induced Stomatitis-A Case Report

Denture Induced Stomatitis-A Case Report

Management of Chronic Atrophic Candidiasis (Denture Stomatitis)—A Narrative Review

Effects of trimethylsilane plasma coating on the hydrophobicity of denture base resin and adhesion of Candida albicans on resin surfaces

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