Candida albicans sternal wound infections among elderly veterans: a chronic and recurrent complication of median sternotomy

Malani, Preeti N.; McNeil, Stephen; Bradley, Suzanne F.; Kauffman, Carol A.

doi:10.1016/s1201-9712(02)90295-x

Cited by 14 publications

(24 citation statements)

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“…4,5 In addition, although post-sternotomy mediastinitis due to Candida albicans is infrequent, it commonly has a chronic and recurrent course. 6 In the present case, however, we did not isolate any fungi from the sternotomy discharge.…”

Section: Literature Reviewcontrasting

confidence: 67%

Recurrent post-sternotomy mediastinitis

Falagas

Rosmarakis

2006

Journal of Infection

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Section: Literature Reviewcontrasting

confidence: 67%

Recurrent post-sternotomy mediastinitis

Falagas

Rosmarakis

2006

Journal of Infection

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“…Currently, amphotericin B deoxycholate is not the first option. Some authors1 12 propose the use of itraconazole in combination with liposomal amphotericin B (as antagonism is observed with the combination of fluconazole and amphotericin B). Use of fluconazole from the beginning of treatment is still controversial.…”

Section: Discussionmentioning

confidence: 99%

“…Candida is a ubiquitous organism whose pathogenicity is enhanced by the involvement of individual defence mechanisms 1 2. Candidemia has frequently been diagnosed after oesophageal/mediastinal surgery; however, the bone and joint involvement associated with vitreous infection by this agent are rare.…”

Section: Introductionmentioning

confidence: 99%

Candida albicansosteomyelitis as a cause of chest pain and visual loss

et al. 2015

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Candida albicans osteomyelitis is a rare disease that occurs in immunocompromised individuals, sometimes with a late diagnosis related to the mismatch between symptoms and candidemia. This case refers to a 36-year-old male patient with a history of oesophageal surgery for achalasia with multiple subsequent surgeries and hospitalisation in the intensive care unit for oesophageal fistula complication. Four months after discharge, the patient was admitted to the infectious diseases department with pain in the 10th-12th left ribs, swelling of the 4th-6th costal cartilage and decreased visual acuity. An MRI study showed thickening and diffuse enhancement, with no defined borders in the cartilage and ribs, compatible with infection. After performing a CT-guided bone biopsy, isolated C. albicans sensitive to antifungal agents was detected. The patient started therapy with liposomal amphotericin B and maintenance fluconazole for 6 months and showed clinical and radiological improvement within this time.

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“…In endemic areas Mycobacterium tuberculosis infection may occur both as a primary event [11] and disseminated bacille CalmetteGuérin infection postvaccination may involve the sternum [12]. Rarer causative organisms include Aspergillus fumigatus in the immunocompromised patient [13] and Candida albicans seen in debilitated patients poststernotomy [14]. Pseudomonas species have been isolated from IV drug users [1].…”

Section: Discussionmentioning

confidence: 99%