Candida albicans Cervical Lymphadenitis in Patients Who Have Acute Myeloid Leukemia

Alsan, Marcella; Issa, Nicolas C.; Hammond, Sarah P.; Milner, Danny A.; DeAngelo, Daniel J.; Baden, Lindsey R.

doi:10.1016/j.clml.2011.06.002

Cited by 8 publications

(2 citation statements)

References 11 publications

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“…Однако морфологически вокруг кандид описывается гнойное, а не гранулематозное воспаление [4,13]. Авторы обращают внимание, что поражение внутренних органов возможно даже без фунгемии [14], что также было особенностью описанного клинического случая.…”

Section: проблемы инфекций в онкогематологииunclassified

Generalized granulomatous inflammation caused by <i>Candida lusitaniae</i> in a patient with myelofibrosis

2019

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В настоящей статье описывается клинический случай, демонстрирующий сложности прижизненной и посмертной диагностики у пациента с первичным миелофиброзом, осложненным генерализованной грибковой инфекцией, вызванной редким возбудителем Candida lusitaniae. Ведение таких пациентов в непрофильном стационаре при отсутствии результатов трепанобиопсии костного мозга и многообразие клинических ситуаций, при которых могут определяться такие проявления, как нейтрофильный лейкоцитоз со сдвигом влево без значительного уменьшения количества эритроцитов и тромбоцитов совместно с генерализованной лимфаденопатией и визуализацией вторичных очагов во внутренних органах, вызывает особое затруднение, становясь причиной неверной тактики лечения. Наслоение нескольких патологических процессов друг на друга (гранулематозное воспаление, очаги экстрамедуллярного кроветворения и обширные некротические изменения) затрудняет даже посмертную верификацию диагноза.

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Section: проблемы инфекций в онкогематологииunclassified

Generalized granulomatous inflammation caused by <i>Candida lusitaniae</i> in a patient with myelofibrosis

2019

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“…In addition, hospital-acquired infections by C. albicans have become a cause of major health concerns. Patients with AML developed cervical lymphadenitis and chronic disseminated infection due to C. albicans [10]. C.albicans appendicitis was reported in a neutropenic patient after induction chemotherapy [11].…”

Section: Introductionmentioning

confidence: 99%

Candida spp Complications in Acute Myeloid Leukemia Patients in Erbil City

Hamsaeed

Muhammad

2022

Al-Kitab J. Pure Sci.

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This study has been carried out in Erbil City -Iraq, 30 patients were diagnosis by flow cytometry as AML which they were admitted to Nanakaly Hospital for Blood Disease and submitted to chemotherapy. Number of adults/children 22 (73.3%) / 8 (26.7%), female / male 13 (43.3%) / 17(56.7%). Only 20 (66.7%) patients were smoker. The highest number was subtyping M4 10 (33.3%) patients, followed by M1 7(23.3%), M3 6(20%), M2 were 3(10%) patients. M5 and M6 were 2 (6.7%). Ten candida spp isolates before induction phase chemotherapy show 9(90%) C.albicans, 1(10%) C. lusitaniae, and from 32 isolates after induction phase chemotherapy, 17(53.1%) C.albicans, 7(21.9%) C. lusitaniae, and 8(25%) C.famata. According to the site of infection, before starting chemotherapy 8(88.9%) C. albicans isolates were in the oral cavity and 1(11.1%) on the skin, while C. lusitaniae was 1 (100%) in oral cavity only. While after chemotherapy 12(70.6%) C.albicans in the oral cavity and 5(29.4%) on the skin, C. lusitaniae was 2 (28.6%) in the oral cavity and 5(71.4%) on the skin, while all C. famata was 8 (100%) on the skin The immunophenotype shows that the number and percentage of patients which the myeloid cells expressed cyMPO was 27(90) with mean percentage of positivity 59.38, while all patients expressed CD33 and CD13 on their blast cell 30(100) with a mean percentage of positivity 59.81 and 30.83 respectively.

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Cytarabine/daunorubicin

2016

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Candida albicans Cervical Lymphadenitis in Patients Who Have Acute Myeloid Leukemia

Cited by 8 publications

References 11 publications

Generalized granulomatous inflammation caused by <i>Candida lusitaniae</i> in a patient with myelofibrosis

Generalized granulomatous inflammation caused by <i>Candida lusitaniae</i> in a patient with myelofibrosis

Candida spp Complications in Acute Myeloid Leukemia Patients in Erbil City

Cytarabine/daunorubicin

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