Cancer Transmission Through Corneal Transplantation

Abstract

There was no increased incidence of cancer in our patient population compared with reference population. Based on this study, there is no statistical or clinical evidence to suggest the transmission of cancer from donors with malignancies via corneal transplantation, according to the accepted criteria of donor selection.

Conjunctival melanoma following cornea transplant from a cancer donor: A case report

“…Corneas from donors with systemic malignancies are usually accepted for transplantation. Salame et al 6 looked at those receptors and found no difference in cancer occurring in the recipients after receiving a cornea from a donor with cancer. In a second study, the corneas of patients dying from cancer without any macroscopic evidence of ocular infiltration were evaluated, and the receivers were followed up for 5 years.…”

“…Cancer transmission through corneal transplantation has been reported before, although it seems to be very rare. 5 , 6 …”

Transplanted Corneal Graft With Metastatic Cholangiocarcinoma to the Donor Eye

“…5,8,9 Few cases of transmission of malignancy secondary to corneal transplantation were reported. In 1939, Hata 10 reported a case that glioma was transmitted from the donor to a recipient.…”

Donor Selection, Retrieval and Preparation of Donor Tissue

“…Recipients of corneal tissue obtained from donors with malignancies do not have a higher risk of cancer than patients in the general population [31][32][33]. There is no evidence from reported clinical studies that recipients of corneal tissue obtained from eyes with choroidal melanoma have a higher risk of developing melanomas [31].…”