Cancer survival differences between South Asians and non-South Asians of England in 1986–2004, accounting for age at diagnosis and deprivation

Abstract

Background:South Asian migrants show lower cancer incidence than their host population in England for most major cancers. We seek to study the ethnic differences in survival from cancer.Methods:We described and modelled the effect of ethnicity, time, age and deprivation on survival for the five most incident cancers in each sex in South Asians in England between 1986 and 2004 using national cancer registry data. South Asian ethnicity was flagged using the validated name-recognition algorithm SANGRA (South Asian Names and Group Recognition Algorithm).Results:We observed survival advantage in South Asians in earlier periods. This ethnic gap either remained constant or narrowed over time. By 2004, age-standardised net survival was comparable for all cancers except three in men, where South Asians had higher survival 5 years after diagnosis: colorectal (58.9% vs 53.6%), liver (15.0% vs 9.4%) and lung (15.9% vs 9.3%). Compared with non-South Asians, South Asians experienced a slower increase in breast and prostate cancer survival, both cancers associated with either a screening programme or an early diagnosis test. We did not find differential patterns in survival by deprivation between both ethnicities.Conclusions:Considering recent survival trends, appropriate action is required to avoid deficits in cancer survival among South Asians in the near future.

Impact of deprivation on breast cancer survival among women eligible for mammographic screening in the West Midlands (UK) and New South Wales (Australia): Women diagnosed 1997–2006

“…However, these tumours represent only 1% of breast cancers registered, so this will have a minimal impact upon our results overall. By contrast, in West Midlands the proportion of non‐White women registered with breast cancer is nearer 4%, but we have shown that, after accounting for deprivation, the survival of the Asian and Black women is not different to that of White women …”

“…By contrast, in West Midlands the proportion of non-White women registered with breast cancer is nearer 4%, but we have shown that, after accounting for deprivation, the survival of the Asian and Black women is not different to that of White women. 21,22 Overall, survival were high for the cohort of women examined. As a consequence, there were a relatively small number of deaths which precluded modelling the effect of screening status and deprivation on survival simultaneously.…”

Proposed biosimilar pegfilgrastim (LA-EP2006) compared with reference pegfilgrastim in Asian patients with breast cancer: an exploratory comparison from two Phase III trials

“…The need for well-controlled clinical studies is particularly important given the increasing incidence of breast cancer in Asian patients [6] and evidence that Asian patients may be more likely to die from breast cancer than other populations [7,13,14]. Evidence also suggests that patients are not treated according to international guidelines in some Asian populations [15,16], and there is a shortage of recommendations for use of G-CSF in Asian patients.…”

“…All but two of the patients in our study were based in India and Malaysia and as such represent two different patient populations, which in turn will differ to the Chinese and Japanese patients in the Zhang and Masuda studies. Evidence regarding breast cancer risk, prevalence and mortality from other continents suggests that Asian women in Western countries may be exposed to lifestyle factors that influence breast cancer incidence [18], and have differences in prevalence and mortality compared with other ethnic groups [7,13,14,19,20].…”

Survival Rate of Prostate Cancer in Asian Countries: A Systematic Review and Meta-Analysis

“…The included studies were published from 1998 to 2018. Based on geographical locations, nine studies were conducted in Korea [19,20,21,30,31,32,33,34,35], five in China [18,36,[37][38][39], five in Japan [40][41][42][43][44], four in India [45][46][47][48], four in Thailand [49][50][51][52], two in Singapore [53,54], two in Taiwan [55,56], one in Hong Kong [57], one in the Philippines [58], one involved Chinese residents in Singapore [59], one involved countries (China, India and Singapore) [60], one involved the Asian population in England [61]. Characteristics of the included studies are presented in Table 1.…”