Cancer-Related Fatigue and Sleep Disorders

Abstract

Sleep disorders, such as difficulty falling asleep, problems maintaining sleep, poor sleep efficiency, early awakening, and excessive daytime sleepiness, are prevalent in patients with cancer. Such problems can become chronic in some patients, persisting for many months or years after completion of cancer therapy. For patients with cancer, sleep is potentially affected by a variety of factors, including the biochemical changes associated with the process of neoplastic growth and anticancer treatments, and symptoms that frequently accompany cancer, such as pain, fatigue, and depression.Fatigue is highly prevalent and persistent in patients with cancer and cancer survivors. Although cancerrelated fatigue and cancer-related sleep disorders are distinct, a strong interrelationship exists between these symptoms, and a strong possibility exists that they may be reciprocally related. The majority of studies that have assessed both sleep and fatigue in patients with cancer provide evidence supporting a strong correlation between cancer-related fatigue and various sleep parameters, including poor sleep quality, disrupted initiation and maintenance of sleep, nighttime awakening, restless sleep, and excessive daytime sleepiness. This paper reviews the data from these studies with a view toward suggesting further research that could advance our scientific understanding both of potential interrelationships between sleep disturbance and cancer-related fatigue and of clinical interventions to help with both fatigue and sleep disturbance. The Oncologist 2007;12(suppl 1): [35][36][37][38][39][40][41][42]

Kualitas Tidur Pasien Kanker Payudara Berdasarkan Terapi yang Diberikan di RSUP DR. Hasan Sadikin Bandung

“…Hasil ini memiliki kesamaan dengan penelitian Araújo et al (2014), bahwa pasien kanker payudara membutuhkan waktu 38 menit untuk mulai tertidur. Begitu pula menurut Roscoe et al (2007), pada 300 pasien kanker yang mengalami insomnia, 76% bangun beberapa kali pada malam hari, 44% mengalami susah tertidur, 35% bangun tengah malam untuk waktu yang lama dan 33% bangun pagi-pagi sekali.…”

Integrative Nonpharmacologic Behavioral Interventions for the Management of Cancer-Related Fatigue

“…Although patients with CRF frequently report disruptions in their sleep patterns, the relationship between sleep patterns and CRF is not well understood [168,169]. Healthcare professionals frequently recommend rest and sleep for the management of CRF [168].…”

Cancer-Related Fatigue: Causes, Consequences, and Management

“…As pointed out by Roscoe et al [20], sleep disorders are a common and often chronic problem for both patients with cancer and cancer survivors, and these problems are strongly linked to CRF. Further investigation is warranted in order to better understand the nature of sleep disturbances in patients with cancer and to examine the effectiveness of interventions targeting disordered sleep and daytime sleepiness, both because they are troublesome symptoms in their own right and also as potential treatments for CRF.…”

“…Multidimensional CRF measures may be useful in assessing physical, emotional, and cognitive domains. In a related vein, the articles by Roscoe et al [20], Mustian et al [16], and Ryan et al [21] summarize information showing that fatigue may occur as part of a cluster of symptoms including pain, difficulty sleeping, and perceived muscle weakness. The associations among these symptoms might prompt the development of effective integrated treatment strategies.…”