Cancer Pain

Sharma, Vivek; Leon‐Casasola, Oscar de

doi:10.1016/b978-0-323-08340-9.00023-2

Cited by 2 publications

(2 citation statements)

References 71 publications

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“…A percutaneous epidural or intrathecal catheter, an external syringe pump, or a fully implanted intrathecal drug delivery system can all be utilized to give medication. Patients with shorter life expectancies (<3 months) may benefit from epidural therapy using implanted systems such as a catheter or port-a-catch connected to an external patient-controlled analgesia (PCA) pump, while patients with cancer-related pain and longer survival expectancies (>3 months) may benefit from neuraxial therapies using implantable systems as a permanent intrathecal catheter and subcutaneous pump [10]. The likelihood of survival, patient demands, and cost are typically taken into account while choosing a type of device.…”

Section: Central Neuraxial Blocksmentioning

confidence: 99%

“…Other anaesthetics, such as bupivacaine, can be used instead of or in addition to opioids because of their long duration of action, low toxicity, and affordable price. Other agents such as clonidine, ketamine, and neostigmine may enhance analgesia and lower opioid dosages [10]. It is crucial to choose patients carefully and to educate the people who will be caring for patients who receive these infusions [11][12].…”

Section: Central Neuraxial Blocksmentioning

confidence: 99%

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Role of Interventional Techniques in the Management of Cancer Pain

Sharma

Thakur

Thakur³

et al. 2023

Asian Pac J Cancer Care

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Pain is the major cause of morbidity in cancer patients. Interventional techniques should be considered for the management of pain that is refractory to traditional analgesics or when patients are unable to tolerate opioids. Interventional techniques are intended to stop pain signals through neural pathways from the periphery to the brain. This article deals with major interventional pain management techniques such as central neuraxial block, sympathetic block, peripheral nerve block, percutaneous cordotomy, percutaneous vertebroplasty and kyphoplasty, radiofrequency ablation, and cryoablation. Besides this, the role of radiotherapy and radionuclides in cancer pain have also been discussed. Central neuraxial block can effectively reduce pain while preventing opioid toxicity. It involves a percutaneous epidural or intrathecal catheter, an external syringe pump, or a fully implanted intrathecal drug delivery system to give medication. Sympathetic blocks such as celiac plexus and superior hypogastric block have role in patients with visceral abdominal pain. Peripheral nerve blocks may be employed when the distribution of somatic pain is restricted to a single nerve or plexus. Percutaneous cordotomy could be useful for any unilateral cancer pain below C4 dermatome. Percutaneous vertebroplasty (PV) treatment is used to alleviate axial back pain due to osteoporotic wedge fracture or malignant vertebral body disease. RFA and cryoablation techniques are now widely used for back pain due to osteoporotic and malignant vertebral collapse that are resistant to conservative treatment. External beam radiotherapy and radionuclides are useful in relieving cancer pain due to bone metastasis. This article aims at summarizing the indications, mechanisms, drug agents, contraindications, and complications of interventional pain management techniques that may offer benefits to patients coping with cancer and its terrible symptoms. Even though there is some risk involved with the techniques discussed in this article, the advantages of reduced pain and enhanced quality of life usually outweigh the risk.

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Section: Central Neuraxial Blocksmentioning

confidence: 99%

Section: Central Neuraxial Blocksmentioning

confidence: 99%