Cancer Medicine and Precision Oncology

Chin-Yee, Benjamin

doi:10.1007/978-94-017-8706-2_115-1

Handbook of the Philosophy of Medicine 2024

DOI: 10.1007/978-94-017-8706-2_115-1

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Cancer Medicine and Precision Oncology

Benjamin Chin-Yee

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2024

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References 55 publications

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Minimal residual disease: premises before promises

Chin-Yee

2024

Biol Philos

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Minimal residual disease (MRD), a measure of residual cancer cells, is a concept increasingly employed in precision oncology, touted as a key predictive biomarker to guide treatment decisions. This paper critically analyzes the expanding role of MRD as a predictive biomarker in hematologic cancers. I outline the argument for MRD as a predictive biomarker, articulating its premises and the empirical conditions that must hold for them to be true. I show how these conditions, while met in paradigmatic cases of MRD use in cancer, may not hold across other cancers where MRD is currently being applied, weakening the argument that MRD serves as an effective predictive biomarker across cancer medicine.

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Minimal residual disease: premises before promises

Chin-Yee

2024

Biol Philos

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scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.

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Cancer Medicine and Precision Oncology

Cited by 1 publication

References 55 publications

Minimal residual disease: premises before promises

Minimal residual disease: premises before promises

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