Cancer in the time of COVID-19: expert opinion on how to adapt current practice

Raskin, Jo; Lebeer, Marnix; Bondt, Charlotte De; Wener, Reinier; Janssens, Annelies; Meerbeeck, Jan P. van

doi:10.1183/13993003.00959-2020

Cited by 17 publications

(23 citation statements)

References 10 publications

(8 reference statements)

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“…De forma particular, el diagnóstico incidental de lesiones tumorales torácicas en pacientes con infección por SARS-CoV-2 supone un desafío adicional, tanto desde el punto de vista diagnóstico como terapéutico. Aunque existen algunas publicaciones que abordan el manejo clínico de los pacientes con cáncer en la pandemia actual de SARS-CoV-2, no existen guías específicas con respecto a la realización de procedimientos de intervencionismo torácico diagnóstico en pacientes con lesiones tumorales y que además están infectados con SARS-CoV-2 [2][3][4][5][6][7][8][9][10][11][12] . Presentamos dos casos en los que se detectaron lesiones tumorales torácicas que requirieron ser biopsiadas, con control radiológico, en el pico de la pandemia de COVID-19 que asolaba Madrid en la segunda quincena de marzo de 2020.…”

Section: Covid-19: Thoracic Diagnostic Interventional Procedures In Tunclassified

COVID-19: intervencionismo diagnóstico torácico en tiempos difíciles

Gorospe

Ayala-Carbonero

Ureña-Vacas

et al. 2020

Archivos de Bronconeumología

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Section: Covid-19: Thoracic Diagnostic Interventional Procedures In Tunclassified

COVID-19: intervencionismo diagnóstico torácico en tiempos difíciles

Gorospe

Ayala-Carbonero

Ureña-Vacas

et al. 2020

Archivos de Bronconeumología

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“…The presence of COVID-19 in such patients often leads to lung swelling, retention of fluid waste, and cellular growth in the lining of the air sacs. Moreover, COVID-19 is established to impact the respiratory lining of the lungs and thoracic region, frequently eliciting symptoms such as dyspnea and cough [ 8 ]. Even in remission, these cancer patients are at higher risk of complications secondary to a COVID-19 infection [ 8 , 9 ].…”

Section: Discussionmentioning

confidence: 99%

“…Moreover, COVID-19 is established to impact the respiratory lining of the lungs and thoracic region, frequently eliciting symptoms such as dyspnea and cough [ 8 ]. Even in remission, these cancer patients are at higher risk of complications secondary to a COVID-19 infection [ 8 , 9 ]. Nevertheless, respiratory complaints, such as those delineated above, remain ubiquitous in this patient population.…”

Section: Discussionmentioning

confidence: 99%

Coronavirus Disease 2019 Presenting as Abdominal Distension in a Mesothelioma Patient: Do We Need to Think Outside the Box?

Irfan¹,

Almas²,

Ullah³

et al. 2020

Cureus

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The coronavirus disease 2019 (COVID-19) remains a major source of mortality globally. Although it usually presents with flu-like symptoms such as fever and sore throat, the intensity of the symptoms varies, constituting a spectrum ranging from asymptomatic to severe cases of acute respiratory failure. The highest proportion of severe cases occurs in older individuals and in those who have underlying health conditions and chronic comorbidities. We chronicle an atypical case of a 46-year-old male with stage IV mesothelioma who presented exclusively with complaints of acute abdominal pain and distension. Despite his cancer status, the patient’s respiratory functions remained unremarkable, accentuating the peculiarity of the case.

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“…The statement also concluded that it could be acceptable to delay the surveillance CT scan for approximately three to six months for patients with an incidentally detected pure GGN of any size, a partially solid lung nodule with a solid component of 6 to 8 mm, or a solid nodule that was less than 8 mm in diameter [10] . Raskin J et al [11] recommended delaying surgery for up to three months in cases of small-size NSCLC that did not appear to grow rapidly, and the growth rate should be followed with chest CT scans. These guidelines propose potential approaches to reduce the risk of COVID-19 infections in NSCLC patients.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of non-small cell lung cancer treatment strategies in a region of China with low-risk for COVID-19

Cheng

2020

Preprint

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Purpose This study analyzed the morbidity and mortality associated with non-small cell lung cancer (NSCLC) and evaluated treatment strategies for it in a low-risk area of COVID-19 in China. Materials and methods: We selected patients admitted to Sichuan Science City Hospital from September 2019 to February 2020 and divided them into experimental and control groups. The treatment strategy was evaluated by patients’ prognosis. Results: 9,010 patients were hospitalized. The total morbidity was 0.699%, of which 0.504% was observed in the control group and 0.991% in the experimental group (P=0.024). The total mortality was 0.999/103, of which 0.630/103 was observed in the control group and 1.413/103 in the experimental group (P=0.322). Therapy discontinuation and cancer progression in the experimental group were significantly higher than the control group (P＜0.001, P=0.007). The treatment methods and prognosis were not significantly different for early-stage patients between the two groups. Late-stage patients in the experimental group experienced significantly lower percentages of non-surgical treatments (P＜0.001), higher percentages of discontinued therapies (P＜0.001), lower percentages for prognosis of wellness (P＜0.001), and higher percentages of cancer progression (P＜0.001) than the control group. Conclusion: NSCLC exhibited significantly higher morbidities during the COVID-19 pandemic. The mortality in the experimental group was slightly higher than the control group, while the difference in cancer progression was significant. It is feasible to perform surgery for early-stage NSCLC patients, and treatment should not be suspended for late-stage patients in regions with low-risk for COVID-19 infection.

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Cancer in the time of COVID-19: expert opinion on how to adapt current practice

Cited by 17 publications

References 10 publications

COVID-19: intervencionismo diagnóstico torácico en tiempos difíciles

COVID-19: intervencionismo diagnóstico torácico en tiempos difíciles

Coronavirus Disease 2019 Presenting as Abdominal Distension in a Mesothelioma Patient: Do We Need to Think Outside the Box?

Evaluation of non-small cell lung cancer treatment strategies in a region of China with low-risk for COVID-19

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