Cancer in Saudi Arabia

Sebai, Zohair A.

doi:10.5144/0256-4947.1989.55

Cited by 26 publications

(28 citation statements)

References 20 publications

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“…A similar observation was made in Saudi Arabia, where a lower incidence was found in the city of Jeddah, possibly due to modernization. 9 It is likely that the incidence of gastric carcinoma in Oman is higher than we have recorded. Some patients from the Dhahira region are probably missing and a few Omanis take themselves abroad for treatment, although they usually appear at some time in the local hospitals for follow-up.…”

Section: Discussioncontrasting

confidence: 46%

“…6 Although gastric carcinoma has been decreasing by about 2% per year in developed countries over the past 50 years, it still accounts for one-fourth to one-half of all new carcinomas in the Eastern hemisphere and is of interest to epidemiologists. [6][7][8][9] It has long been thought that gastric carcinoma is the most common carcinoma in Oman, but to date no studies have been presented to determine the incidence of this tumor. The present study was conducted to document the annual number of cases, their geographic locations, treatment, staging and types of gastric carcinoma; it was retrospective over a two-year period from November 1987 to November 1989.…”

Section: Discussionmentioning

confidence: 99%

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Gastric Carcinoma in the Sultanate of Oman: Incidence and Distribution

et al. 1996

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Gastric carcinoma has always been considered a major problem in the Sultanate of Oman. This study was conducted to document the cases in Oman over a two-year period, in order to determine incidence, age, sex and geographical distribution of the condition. All cases of gastric carcinoma in Omani nationals presenting to the medical facilities throughout Oman from November 1987 to November 1989 were reviewed from pathology records, surgical database records and by personal communication with surgeons at regional hospitals. Specimens taken at surgery or endoscopic biopsy were examined and classified according to Lauren's criteria. Over the two-year period, 104 cases of gastric carcinoma were observed. This represented an annual incidence of 4.2/100,000 population, but when adjusted to the standard European population age distribution (in the Oman population, 51% are under 15 years of age), the incidence was 8.6/100,000. The male:female ratio was 1.6:1 and the peak age group was 60-69. All tumors were advanced and most were located in the antral part of the stomach. There were more intestinal types of tumors than diffuse and a preponderance of intestinal metaplasia. This first survey of stomach carcinoma in Oman will provide a reference for future studies and indicates the need for earlier detection.

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Section: Discussioncontrasting

confidence: 46%

Section: Discussionmentioning

confidence: 99%

Gastric Carcinoma in the Sultanate of Oman: Incidence and Distribution

et al. 1996

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“…[3][4][5] In Saudi Arabia, several retrospective observational studies 6,7 and a recent review 8 have shown that breast cancer is the most common cancer type in Saudi females, constituting about 17% of all malignancies. Despite its high prevalence, the attitude of local physicians and that of asymptomatic females toward screening mammography has not been assessed.…”

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confidence: 99%

Retrospective Appraisal of 300 Consecutive Mammograms

et al. 1990

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Based on certain selection criteria, 300 consecutive mammograms were reviewed, together with other relevant clinical and pathological data. The median age (± SD) of eligible women was 36.11 (± 11.2 years). Saudis represented 65% (196 women) of the study population and non-Saudis 35% (104 women). Seventy-three women (24%) had normal findings but fibrocystic disease was found in 177 (59%), invasive carcinoma in 26 (9%), and fibroadenoma in 24 (8%). Ninety-nine percent of the mammograms were ordered in women who had had breast symptoms for several months. Cancer patients had been aware of their breast lump for a mean of 8.04 ± 2.11 (SD) months. All cancers were invasive and most (92.3%) were advanced at diagnosis. Among the 177 patients with fibrocystic disease, only six (3%) were found to have atypical hyperplasia, but its prevalence is lower than that reported recently. Agreement between final and mammographic diagnoses was significant (P = 0.027). Also shown were the high specificity (79%), sensitivity (100%), and accuracy (89%) of mammograms in cancer patients. The ability of mammography to show malignancy was proven by multiple regression analysis. Our data taken from a sample of women seen at a tertiary care facility shed some light on the pattern of breast disorders in our patient population. The data should be utilized in the planning for a national breast cancer early detection program.AY El-Hassan, FA Al-Mulhim, EM Ibrahim, MS Al-Awami, Retrospective Appraisal of 300 Consecutive Mammograms. 1990; 10(3): 285-290 Radiographic examination of the breast is not a new procedure. The first mammographie study was made by Salomon in 1913 and the first clinical paper on the subject was published in 1930 by Warren.1 Since then, mammography has proved its value in the diagnosis of various breast diseases. However, it was not until 1956 that the procedure was introduced for the mass screening of healthy women in the early detection of breast cancer. 2Analysis of data derived from these major screening projects has shown an unequivocal benefit for women older

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“…1,3 This should not adversely affect our knowledge of the different aspects of the disease, because we anticipate a gradual increase in the number of prostate cancer cases as other cancer cases increase. 8 The high incidence of stage D (55%) may indicate that prostatic carcinoma was not detected early due to lack of periodic screening with DRE and serum PSA determinations. Even within this series, only 50% of the patients had had PSA determination.…”

Section: Discussionmentioning

confidence: 99%

“…However, until recently we lacked the proper means for the accurate diagnosis of certain diseases, and even if cases of prostate cancer were diagnosed, they may not have been sufficiently reported. 8,9 A review of the available literature on this subject has recently been provided. 10 The purpose of this current study is to add more information on prostate cancer in Saudi Arabia.…”

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confidence: 99%

Prostate Cancer: Experience at King Abdulaziz University Hospital, Jeddah

Mosli

1997

Ann Saudi Med

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This paper presents the experience of King Abdulaziz University Hospital (KAUH) in Jeddah, Saudi Arabia, with prostatic cancer patients seen over a period of more than ten years (1986)(1987)(1988)(1989)(1990)(1991)(1992)(1993)(1994)(1995)(1996)(1997). Fifty-five patients with confirmed diagnosis of prostate cancer were identified at KAUH during this period. Forty-seven presented primarily to KAUH and eight were referred from other centers for management and/or follow-up. Data analyzed included age at presentation, ethnic origin, mode of presentation, result of digital rectal examination (DRE), results of serum tumor markers, prostatic acid phosphatase, or prostatic specific antigen (PSA), results of transrectal ultrasonographic scan of the prostate (TRUS), methods and results of prostate biopsy, pathological grade of the cancer tissues, the clinical staging, and finally the type of treatment used. The average age at presentation was 68.8 years. Forty-one patients were white, six were black and the ethnic origin was not determined in eight patients. The main clinical presentation was by symptoms of prostatism in 36 patients (65%). DRE revealed benign prostatic hyperplasia (BPH) in 31 patients (56%) and suspicion of cancer in 24 (44%). Of the patients with adenocarcinoma of the prostate, 27 had PSA measurements, elevated above 20 ng/mL in 17 (63%). The tissues were obtained from the prostate by needle biopsy in 30 patients (transperineal approach in 17 and TRUS-guided in 13 patients), prostatectomy in 17 patients (open in one, and transurethral prostatic resection in 16 patients), and unspecified method in eight patients. TRUS performed on 18 patients showed hypoechoic nodules indicative of cancer in 11 patients and BPH or normal in seven patients. Clinical staging revealed 15 (27%) in stage A, 5 (9%) in stage B, 5 (9%) in stage C and 30 (55%) in stage D. During this period no retropubic radical prostatectomy operation aimed at curing localized prostate cancer was performed at KAUH, while bilateral orchiectomy for control of metastatic disease was done for 12 patients, and 18 patients received endocrine therapy. Ann Saudi Med 1997; 17(6):590-594.

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Cancer in Saudi Arabia

Cited by 26 publications

References 20 publications

Gastric Carcinoma in the Sultanate of Oman: Incidence and Distribution

Gastric Carcinoma in the Sultanate of Oman: Incidence and Distribution

Retrospective Appraisal of 300 Consecutive Mammograms

Prostate Cancer: Experience at King Abdulaziz University Hospital, Jeddah

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