1998
DOI: 10.1002/(sici)1097-0142(19981001)83:7<1275::aid-cncr1>3.0.co;2-i
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Cancer epidemiology 50 years later

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“…The introduction of PSA testing in the late 1980s and its expanded utilization in the 1990s is credited with the increased early detection and "stage shift" toward early-stage, potentially curable disease at diagnosis (Burack & Wood, 1999;Mettlin, 1998;Mettlin & Murphy, 1998;Mettlin, Murphy, Babaian, et al, 1997). PSA screening also has been credited for recent declines in mortality (Mettlin, 1998;Mettlin & Murphy, 1998), although this assertion is a subject of debate and further investigation. Whereas controlled studies are currently under way to determine whether screening with PSA test and DRE reduces overall mortality, epidemiologic evidence suggests that PSA screening is effective in the early detection of clinically significant prostate cancer.…”
Section: > Screening Guidelinesmentioning
confidence: 99%
“…The introduction of PSA testing in the late 1980s and its expanded utilization in the 1990s is credited with the increased early detection and "stage shift" toward early-stage, potentially curable disease at diagnosis (Burack & Wood, 1999;Mettlin, 1998;Mettlin & Murphy, 1998;Mettlin, Murphy, Babaian, et al, 1997). PSA screening also has been credited for recent declines in mortality (Mettlin, 1998;Mettlin & Murphy, 1998), although this assertion is a subject of debate and further investigation. Whereas controlled studies are currently under way to determine whether screening with PSA test and DRE reduces overall mortality, epidemiologic evidence suggests that PSA screening is effective in the early detection of clinically significant prostate cancer.…”
Section: > Screening Guidelinesmentioning
confidence: 99%
“…Proponents of routine screening have pointed to recent declines in prostate cancer mortality as evidence of the benefits of routine screening, early detection, and early treatment (Mettlin, 1998;Mettlin & Murphy, 1998). There is growing consensus that as we await evidence from controlled trials, all men including those at high risk, must be counseled with balanced information that discusses both the potential benefits and harms of testing to make an informed decision about whether to be tested or not (ACS, 2008;Lin et al, 2008;USPSTF, 2002USPSTF, , 2008.…”
Section: Introductionmentioning
confidence: 99%