Cancer du sein au Cameroun, profil histo-épidémiologique: à propos de 3044 cas

Engbang, Jean Paul; Henri, Essome; Koh, Valère Mve; Godefroy, Simo; Essam, Jean Daniel Sime; Mouelle, Albert Soné; Essame, J. L.

doi:10.11604/pamj.2015.21.242.7269

Cited by 19 publications

(35 citation statements)

References 10 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…As for age, the extremes ranges from 18 and 88 years old, with an average age of 47 ± 11 years. These results are comparable to those found in Cameroon [4].…”

Section: Discussionsupporting

confidence: 90%

“…Histologically, there was a preponderance of infiltrating ductal carcinomas with 94%, followed by infiltrating lobular carcinoma with 3.7% and metaplastic carcinoma with 1.7%. These results are comparable to the Moroccan and Cameroonian series but with different proportions [4] [18].…”

Section: Discussionsupporting

confidence: 84%

“…In our series, breast cancer was common in both patients before and after 50 years. The most represented age groups were respectively 33 -47 years old with 45.5% and 48 -62 years old with 39% while in the Cameroonian series 17% of the patients were between 45 -49 years old [4]. In Niger, Zaki et al found 69.89% of breast cancers in women before age 50 [7].…”

Section: Discussionmentioning

confidence: 94%

“…In sub-Saharan Africa, the incidence of breast cancer varies by country [4]; in Mali, from 2006 to 2010 it is in second place after the cervix, with a relative frequency of 18.7%, it is the second cause of cancer death after cervical cancer [5].…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Epidemiological and Clinical Profile of Breast Cancer at Bamako Radiotherapy Center

Kone¹,

Diakité²,

Diarra³

et al. 2019

JCT

View full text Add to dashboard Cite

Breast cancer is a major public health problem because of its incidence and mortality. Purpose: To establish the epidemiological and clinical characteristics of breast cancer seen at the radiotherapy center at the Mali Hospital of Bamako. Patients and methods: It was a retrospective, descriptive study of data from patients seen for breast cancer at the Center of Radiotherapy of Mali Hospital between April 2014 and December 2016. The parameters studied were: age, sex, family history of breast cancer, menopausal status, parity, breast tumor location, histological type, histological grade, cancer classification stage. Results: 134 cases of breast cancer were collected, with a frequency of 15%. The sex ratio (H/F) of 0.007. The patient's mean age was 47 ± 11 years old. The most represented age groups were 33-47 years old with 45.5% and 48-62 years old with 39%. Three percent (3%) of patients had a family history of breast cancer. Fifty (50%) of the patients were menopausal. The main clinical signs found were : mammary nodules (98%), mastodynia (65%), nodes (67%). Invasive ductal carcinomas were found in 94% of patients, followed by infiltrating lobular carcinomas with 3.7% and metaplastic carcinomas with 1.7%. SBR Grades II and III were mostly found with 37% and 23%. The average tumor size was 87 mm ± 43. Stage III was predominantly represented with 72%, followed by Stage II with 24% and Stages I and IV with 2% each. Conclusion: Breast cancer is common and reaches both before and after 50 years; the diagnosis is usually late; hence it is the importance of raising awareness and screening before the age of 50 and popularizing some complementary tests to better understand the prognosis of this disease and promote more targeted and conservative treatments that will improve survival.

show abstract

“…As for age, the extremes ranges from 18 and 88 years old, with an average age of 47 ± 11 years. These results are comparable to those found in Cameroon [4].…”

Section: Discussionsupporting

confidence: 90%

Section: Discussionsupporting

confidence: 84%

Section: Discussionmentioning

confidence: 94%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Epidemiological and Clinical Profile of Breast Cancer at Bamako Radiotherapy Center

Kone¹,

Diakité²,

Diarra³

et al. 2019

JCT

View full text Add to dashboard Cite

show abstract

“…Numerous histological studies find infiltrative canalar carcinoma of breast associated with abscess [13, 14]. But none of them thoroughly investigated the association of these two pathologies.…”

Section: Discussionmentioning

confidence: 99%

Breast Abscessed Cancer in Nonlactating Women in Tropical Environment: Radiological, Bacteriological, and Anatomopathological Features about 3 Cases

Tchaou

Darré

Amavi

et al. 2017

Case Reports in Radiology

View full text Add to dashboard Cite

show abstract

Involvement of ERCC1 (rs3212986) and ERCC2 (rs1799793, rs13181) polymorphisms of DNA repair genes in breast cancer occurrence in Burkina Faso

Adico¹,

Zoure

Sombié³

et al. 2023

Molec Gen & Gen Med

View full text Add to dashboard Cite

Background Genetic alterations can result in DNA repair defects, increasing susceptibility to breast cancer. The aim of this study was to evaluate the involvement of two DNA repair genes, ERCC1 ( rs3212986, GenBank NC_000073.9) and ERCC2 ( rs1799793, rs13181 , GenBank: NC_000019.10 ) in the occurrence of breast cancer in Burkina Faso. Methods This case–control study enrolled 128 participants including 64 patients and 64 healthy controls. Genotyping of polymorphisms were performed by real‐time PCR and PCR‐RFLP. Results The heterozygous AC genotype of the ERCC2rs13181 polymorphism was associated with the occurrence of breast cancer when the mutant allele is inherited under the dominant pattern (CC/AC vs AA; OR = 2.74, 95% IC (1.09–6.87); p = .028), but this association became insignificant after the Bonferroni correction ( p = .156). No association was observed between ERCC1 rs3212986 and ERCC2rs1799793 polymorphisms and breast cancer risk. Conclusion This study showed that the heterozygous genotype (CA) of the ERCC2rs13181 polymorphism may be associated with a risk of breast cancer.

show abstract

Cancer du sein au Cameroun, profil histo-épidémiologique: à propos de 3044 cas

Cited by 19 publications

References 10 publications

Epidemiological and Clinical Profile of Breast Cancer at Bamako Radiotherapy Center

Epidemiological and Clinical Profile of Breast Cancer at Bamako Radiotherapy Center

Breast Abscessed Cancer in Nonlactating Women in Tropical Environment: Radiological, Bacteriological, and Anatomopathological Features about 3 Cases

Involvement of ERCC1 (rs3212986) and ERCC2 (rs1799793, rs13181) polymorphisms of DNA repair genes in breast cancer occurrence in Burkina Faso

Contact Info

Product

Resources

About