Cancer de prostate : étude comparative stade T1a et stade T1b

Lefi, Mounir; Hellara, W.; Touffahi, Mounir; Fredj, N. Ben; Moussa, A.; Saidi, Radhwane; Saad, H.

doi:10.1016/s1166-7087(07)78574-3

Cited by 2 publications

(1 citation statement)

References 18 publications

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“…Several studies have reported that stage T1b cancer has a poorer prognosis than stage T1a 12-15. However, Magheli, et al6 reported that a sub-classification of incidental prostate cancer was not an independent predictor of biochemical recurrence after adjustment for PSA, Gleason score, or year of surgery in patients who underwent RP.…”

Section: Discussionmentioning

confidence: 99%

Clinical Experiences of Incidental Prostate Cancer after Transurethral Resection of Prostate (TURP) According to Initial Treatment: A Study of a Korean High Volume Center

et al. 2014

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Purpose These are the clinical experiences of Korean incidental prostate cancer patients detected by transurethral resection of the prostate according to initial treatment: active surveillance (AS), radical prostatectomy (RP) and hormone therapy (HT).Materials and MethodsWe retrospectively reviewed the records of 156 incidental prostate cancer patients between 2001 and 2012. The clinicopathologic outcomes were reviewed and follow-up results were obtained.ResultsAmong 156 patients, 97 (62.2%) had T1a and 59 (37.8%) had T1b. Forty-six (29.5%) received AS, 67 (42.9%) underwent RP, 34 (21.8%) received HT, 4 (2.6%) received radiotherapy, and 5 (3.2%) chose watchful waiting. Of 46 patients on AS, prostate-specific antigen (PSA) progression occurred in 12 (26.1%) patients. Among them, 3 patients refused treatment despite PSA progression. Five patients, who underwent RP as an intervention, all had organ-confined Gleason score ≤6 disease. In 67 patients who underwent RP, 50 (74.6%) patients had insignificant prostate cancer and 8 (11.9%) patients showed unfavorable features. During follow-up, biochemical recurrence occurred in 2 patients. Among 34 patients who received HT, 3 (8.8%) patients had PSA progression. Among 156 patients, 6 patients died due to other causes during follow-up. There were no patients who died due to prostate cancer.ConclusionThe clinical outcomes of incidental prostate cancer were satisfactory regardless of the initial treatment. However, according to recent researches and guidelines, immediate definite therapy should be avoided without a careful assessment. We also believe that improved clinical staging is needed for these patients.

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Section: Discussionmentioning

confidence: 99%