Background: Penile cancer is an unusual malignancy with higher incidence rates in developing countries like India when compared to the Western world. Incidence varies from 0.7-2.3 cases per 100,000 men in urban India and 3 cases per 100,000 men in rural India. In spite of its rarity, it forms a suitable medical model for theranostics. Given this relevance we put forward our departmental experience in a rural Indian setup. Materials and Methods: This is a retrospective three year study of penile SCC patients managed in Indian Red Cross Cancer Hospital, India. Data was compared with similar studies across the world. Results: 23 patients were diagnosed with squamous cell carcinoma of penis during the period of study. We witnessed in this study that a relatively younger age of presentation and early stages prevailing. Higher percentage of involvement of prepuce and body was also noted. Conclusion: Consideration of prognostic histopathological factors may help to tailor appropriate management in this infrequent malignancy.