Cancer control potential of marine natural product scaffolds through inhibition of tumor cell migration and invasion

An Updated Review on Marine Anticancer Compounds: The Use of Virtual Screening for the Discovery of Small-Molecule Cancer Drugs

“…The second most frequent cancer in both men and women is colorectal cancer. Although significant advances are being made against cancer, this disease remains a key public health concern and a tremendous burden on European and American societies [ 2 ]. Every year, the American Cancer Society collects and compiles the most recent surveillance and epidemiology data about cancer (incidence, mortality and survival).…”

“…An increasing number of documents about marine compounds with regard to human health have been published in the last twenty years ( Figure 1 A) in many different areas of knowledge ( Figure 1 B). To date, eight drugs isolated from marine organisms have been approved for different purposes (cytarabine, vidarabine, ziconotide, omega-3 acid ethyl esters, trabectedin, eribulin mesylate, brentuximab vedotin and iota-carrageenan) [ 2 ]. Five of these compounds are obtained from marine invertebrates and have been approved for use as pharmaceutical drugs in cancer treatment.…”

Review of Chromatographic Bioanalytical Assays for the Quantitative Determination of Marine-Derived Drugs for Cancer Treatment

“…For years, researchers have roamed the seas and oceans in search of organisms possessing chemicals that could exhibit therapeutic effects. These include a wide variety of creatures, such as tunicates, mollusks, sponges, bacteria, seaweeds, chordates, mangroves, sea hares, and sharks [ 1 , 2 , 3 ]. Therapeutic indications include cancer, Alzheimer’s disease, thrombosis, hypertension, psoriasis, asthma, and pain [ 4 , 5 , 6 , 7 ].…”

A novel red pigment from marineArthrobactersp. G20 with specific anticancer activity

“…Marine environments cover two-thirds of the planet's surface; they are interesting sources for the identification of novel bioactive compounds. Mudit and El Sayed recently reviewed marine-derived compounds with potential anticancer activities (Mudit and El Sayed 2016). Several of these entities have bacterial sources (Chang et al 2011).…”