Câncer colorretal sincrônico: relato de caso e revisão de literatura

Andrade, Sérgio Murilo da Silva; Pereira, Fábio Lima

doi:10.1590/s0101-98802007000100010

Cited by 10 publications

(11 citation statements)

References 11 publications

(21 reference statements)

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“…Following the blood vessel invasion, tumor cells that resist to the mechanic stress of circulation and to the immune system “colonize” the subcutaneous tissues until they acquire the necessary angiogenic properties and a favorable microenvironment to leave the state of “numbness”. 9 …”

Section: Discussionmentioning

confidence: 99%

Multiple Subcutaneous Nodules Leading to Diagnosis of Colon Cancer

Madabhavi

Kadakol²,

Chavan

et al. 2018

Middle East J Dig Dis

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Skin metastases from colorectal carcinoma are rare and signal advanced disease. Skin metastasis refers to growth of cancer cells in the skin originating from an internal cancer. In most cases, cutaneous metastasis develops after the initial diagnosis of the primary internal malignancy and late in the course of the disease. In very rare cases, skin metastasis may occur at the same time or before the primary cancer has been discovered and may be the prompt for further thorough investigation. The incidence of skin metastasis varies but is somewhere between 3-10% in patients with a primary malignant tumor. Most common ones are melanoma (45%), breast cancer (30%), nasal sinus cancers (20%), cancer of the larynx and cancer of the oral cavity (12%) cases. Here we present a case of 39-year-old man presented to us with multiple subcutaneous lesions over the chest and forehead. Fine needle aspiration cytology of skin nodules revealed metastatic adenocarcinoma features. Further imaging of the abdomen with computed tomography (CT) revealed circumferential narrowing of caecum and ascending colon. The patient was managed with palliative right hemicolectomy in view of constipation and palliative chemotherapy as systemic treatment. An extensive review of the English literature did not reveal extensive data on metastatic subcutaneous nodules leading to diagnosis of colon cancer.

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Section: Discussionmentioning

confidence: 99%

Multiple Subcutaneous Nodules Leading to Diagnosis of Colon Cancer

Madabhavi

Kadakol²,

Chavan

et al. 2018

Middle East J Dig Dis

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“…However, it can also be disseminated by contiguity to the peritoneum or intraabdominal organs 1 ; there are many reports of metastasis to unusual locations.…”

Section: Discussionmentioning

confidence: 99%

“…Colorectal cancer (CRC) is the fourth most common malignant neoplasm in the world, and also the most frequent in the digestive tract, presenting with high mortality rates -about half a million deaths per year 1,2 . According to Andrade and Pereira, the adenocarcinoma responds for 90% of the CRC cases 1 .…”

Section: Introductionmentioning

confidence: 99%

Cutaneous metastases from colonic adenocarcinoma: case report

Gomes¹,

Bin²,

Klug³

et al. 2012

J. Coloproctol. (Rio J.)

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Gomes CMCN; Bin FC; Klug WA; Valois T; Preza MTG. Cutaneous metastases from colonic adenocarcinoma -case report. J Coloproctol, 2012;32(3): 297-300. ABSTRACT:The presence of cutaneous metastases (CM) from a digestive tract cancer is infrequent, appearing in less than 5% of the cases. Given the low incidence of metastasis from colon adenocarcinoma, an unusual case that occurred in the Colorectal Surgery Department of Santa Casa de São Paulo is described in this report, and a brief review of literature is presented. A 78-year-old female patient who underwent right hemicolectomy, developed a tumor with approximately 8 cm in diameter in her gluteus eight months later, which was surgically resected, and the histological diagnosis was metastatic adenocarcinoma of the right colon. Although the literature estimated short survival in cases of CM, the patient developed no signs of tumor recurrence five months after the onset of metastasis in the gluteus, with significant improvement in her quality of life.Keywords: colonic neoplasms; adenocarcinoma; neoplasm metastasis; skin; neovascularization, pathologic. RESUMO: Metástase cutânea de adenocarcinoma de cólon -relato de caso.A presença de metástase cutânea (MC) de neoplasia de trato digestivo é um evento pouco frequente, presente em menos de 5% dos casos da doença. Tendo em vista a baixa incidência da metástase cutânea de adenocarcinoma de cólon, será descrito no presente relato um caso incomum que ocorreu no Serviço de Coloproctologia do Departamento de Cirurgia da Irmandade da Santa Casa de São Paulo e será feita uma breve revisão de literatura. Uma paciente do sexo feminino, 78 anos, submetida à hemicolectomia direita, desenvolveu após oito meses tumoração de aproximadamente 8 cm de diâmetro em sua nádega, que foi ressecada cirurgicamente, tendo diagnóstico histológico de metástase de adenocarcinoma de cólon direito. Apesar de ser estimada pela literatura uma sobrevida curta nos casos de MC, a paciente evolui sem sinais de recidiva do tumor após cinco meses do surgimento da metástase em

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“…CRC remains as an important cause of morbimortality worldwide 3,4 . In Brazil, the incidence has increased each year 5 .…”

Section: Discussionmentioning

confidence: 99%

“…Colorectal cancer (CRC) is a pathology characterized by tumors in the colorectal segments 1 . In terms of incidence, colorectal cancer is the fourth most frequent cause of cancer in the world and the second cause in developed countries [2][3][4] .…”

Section: Introductionmentioning

confidence: 99%

Questionnaire assessment based on signs, symptoms and history in the prevention of colorectal cancer

Sousa¹,

Fé²,

Monte³

2011

J. Coloproctol. (Rio J.)

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INTRODUCTION: Colorectal cancer (CRC) is an important pathology characterized by tumors in colorectal segments. Colonoscopy is the gold standard of CRC detection, but it is very expensive. Then, new methods are required for CRC screening to reduce mortality and improve the cost-benefit ratio. Objective: Evaluate the efficacy of a questionnaire (QSSA) based on signs and symptoms of CRC. METHODS: The QSSA was answered by 40 patients, before the colonoscopy procedure. The patients were divided into two groups: group I, with 20 patients showing positive result in the questionnaire, and group II, with 20 people showing negative result in the questionnaire. Colonoscopy was considered positive when presenting neoplasm or its precursor. The result was statistically analyzed by Fischer's exact test and sensitivity calculation. RESULTS: The results showed 14 positive and 26 negative colonoscopies. Group I had 9 positive and 11 negative colonoscopies and Group II, 5 positive and 15 negative (p=0.20) colonoscopies. The questionnaire presented sensitivity of 64.2%. CONCLUSION: The use of this questionnaire based on signs and symptoms of CCR alone was not effective in CCR screening.
INTRODUÇÃO: O câncer colorretal (CCR) é uma importante afecção caracterizada pela presença de tumores localizados no colón ou reto. A colonoscopia, padrão ouro na detecção do CCR, demanda alto custo. Assim, há necessidade de métodos de triagem eficazes, visando um melhor custo beneficio na diminuição da mortalidade do CCR. OBJETIVO: Avaliar a efetividade de um questionário de sinais, sintomas e antecedentes (QSSA) em predizer o CCR. Métodos: O QSSA foi aplicado a 40 pacientes, momentos antes da realização do exame colonoscópico, no intuito de compor dois grupos: grupo I formado pelos 20 primeiros que apresentassem o QSSA positivo, e grupo II formado pelos 20 primeiros com QSSA negativo. A colonoscopia positiva foi aquela com achado de neoplasia ou lesões precursoras do CCR. O resultado foi submetido à análise estatística através do Teste Exato de Fischer e do cálculo da sensibilidade, especificidade, acurácia e valores preditivos positivos e negativos. RESULTADO: Observaram-se 14 colonoscopias positivas e 26 colonoscopias negativas, assim distribuídas: grupo I, 9 positivas e 11 negativas; grupo II, 5 positivas e 15 negativas (p=0,20). O questionário apresentou sensibilidade de 64,2%. CONCLUSÃO: A utilização de um questionário de sinais, sintomas e antecedentes usado isoladamente não mostrou eficácia no rastreamento de lesões neoplásicas

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Câncer colorretal sincrônico: relato de caso e revisão de literatura

Cited by 10 publications

References 11 publications

Multiple Subcutaneous Nodules Leading to Diagnosis of Colon Cancer

Multiple Subcutaneous Nodules Leading to Diagnosis of Colon Cancer

Cutaneous metastases from colonic adenocarcinoma: case report

Questionnaire assessment based on signs, symptoms and history in the prevention of colorectal cancer

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