Cancer Biology and Therapeutics: Navigating Recent Advances and Charting Future Directions

Abstract

Cancer, a multifaceted and heterogeneous ailment, persists as a substantial global public health concern. Recent strides in cancer biology have profoundly augmented our comprehension of the intricate genetic and molecular mechanisms underlying the inception and advancement of cancer. This headway has propelled the formulation of innovative therapeutic strategies, embracing targeted interventions and immunotherapies, which have showcased promising outcomes in clinical assessments. However, a multitude of obstacles continue to challenge the creation of efficacious and individualized cancer treatments. This systematic review encapsulates an extensive vista of contemporary advancements in cancer biology and therapeutics, accentuating pivotal breakthroughs in our grasp of cancer's intricacies, while illuminating the latest therapeutic avenues for cancer management. Moreover, the paper elaborates on the quest's upcoming trajectories in cancer research and treatment, encompassing burgeoning technologies and uncharted domains of inquiry that might pave the way for more efficacious and personalized interventions for individuals afflicted by cancer.

Telmisartan loaded lipid nanocarrier as a potential repurposing approach to treat glioma: characterization, apoptosis evaluation in U87MG cells, pharmacokinetic and molecular simulation study

“…Today, clinically approved anticancer drugs have neither succeeded to bring any meaningful impact on glioma therapy nor on quality-of-life post chemotreatment. As a result, incidence of glioma has been turned uncontrollable with bothersome mortality rate across the globe [3,4]. According to a report, roughly 11 000 new cases of GBM will be diagnosed in the United States with each passing year and the incidences might turn uncontrollable by 2040 [5].…”