Cancer and arthritis

Bilateral Femoral and Tibial Periostitis in the La Ferrassie 1 Neanderthal

“…The abnormalities consist of enlargement of the hands and feet with clubbing of the fingers and toes and distal thickening of the soft tissues (Guyer, Brunton & Wren, 1978). Face and skin abnormalities appear as accentuated forehead creases and prominent nasolabial folds accompanied by a rough, thickened, ''greasy'' texture of the skin of the face and the scalp (pachydermia) (Calabro, 1967;Segal & Mackenzie, 1982). Pachydermoperiostosis generally progresses for approximately 10 years before arresting spontaneously, and rarely gives rise to symptoms of illness.…”

“…Scurvy is a connective tissue disease caused by dietary deficiency of vitamin C which produces loss of cortical bone, loss of trabeculation in the long bones and disturbances in bone growth (Cook, 1975). Irritation of the periosteum Calabro, 1967;Cook, 1975;Schumacher, 1976;Steinbock, 1976;Segal & Mackenzie, 1982;Ortner & Putschar, 1985;Baker & Armelagos, 1988;Altman, 1989. For further discussion and references see text.…”

Arthritis as the presenting feature of childhood leukemia

“…T h e e m p h a s i s i n t h e literature has been on bony changes. However, some patients, especially children, have arthritis as their major presenting complaint (8). Early in the course of the disease there may be difficulty in arriving at the correct diagnosis when studies of peripheral blood are not diagnostic.…”

Case of an Acute lymphoblastic Leukemia Presenting as Elbow Septic Arthritis

“…Bu bulgular nonspesifik olup, ateş yüksekliği, hâlsizlik, solukluk, ekstremite ve eklem ağrılarıdır (1) . ALL ço-cuklarda kemik ve ekstremite ağrılarından çok tek veya çoklu eklem tutulumu ile seyretmektedir (8,9) . Olgumuz da üç yaşında erkek hasta olup, sağ dirsek eklemi ağrısı nedeniyle başvurmuştu.…”