Cancer—an ayurvedic perspective

Balachandran, Premalatha; Govindarajan, Rajgopal

doi:10.1016/j.phrs.2004.04.010

Cited by 260 publications

(140 citation statements)

References 48 publications

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“…Piperine extracted from this plant has been used as an ingredient in Ayurvedic formulations because of its antioxidant potency both in vitro and in vivo in mice. [20]. Piperine, due to this antioxidant property, is used topically in a cream base to treat sunburn diseases [21].…”

Section: Piper Longummentioning

confidence: 99%

Herbal Cosmeceuticals for Photoprotection from Ultraviolet B Radiation: A Review

Mishra¹,

Chattopadhyay²

2011

Trop. J. Pharm Res

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Section: Piper Longummentioning

confidence: 99%

Herbal Cosmeceuticals for Photoprotection from Ultraviolet B Radiation: A Review

Mishra¹,

Chattopadhyay²

2011

Trop. J. Pharm Res

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“…Therefore, they have been widely used in treating obesity [5,8,13]. Solanum xanthocarpum fruits are known for several traditional uses as medicine, like anthelmintic, laxative, antipyretic, anti-asthmatic, anti-inflammatory activity and enlargement of liver [14][15][16].…”

Section: Introductionmentioning

confidence: 99%

Evaluation of Anti-Obesity Activity of Solasodine in High Fat Diet-Induced Obesity in Rat

Khaserao

Somani

2017

Int J Pharm Pharm Sci

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Objective: This study was planned to study the anti-obesity activities of solasodine on high fat (HF) diet-induced obese rats.Methods: Wistar rats were divided into six groups. Control group (Group 1) received normal diet and 0.5 % CMC (5 ml/kg). HF control group (Group 2) received HF diet. Group 3 received orlistat (25 mg/kg body weight per oral). Group 4, 5 and 6 received 25, 50 and 100 mg/kg body weight solasodine respectively. Treatment was given for 6 w to the respective group along with HF diet. Body weight, food intake and abdomen circumference was measured every week for 6 w. On day 42, the serum biochemical parameters like blood glucose and insulin, serum leptin, total cholesterol and triglyceride were evaluated. Animals were sacrificed with overdose of diethyl ether. The liver and retroperitoneal adipose tissues were removed and weighed immediately. Results:Treatment with solasodine at dose of 50 mg/kg and 100 mg/kg significantly (p<0.001) reduced body weight, abdomen circumference and retroperitoneal adipose tissue weight as compared to the HF diet control group. Solasodine also significantly reduced serum total cholesterol, triglyceride and glucose level as compared to HF diet control group (***p<0.001, **p<0.01, *p<0.05 when compared with normal control. ###p<0.001, #p<0.05 when compared with high fat control). In addition, it also inhibited the induction of fatty liver with accumulation of hepatic triglyceride. Conclusion:Solasodine exhibited anti-obesity effect by showing a reduction in body weight, abdomen circumference, total cholesterol level, triglyceride level and glucose level in high-fat diet fed rats.

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“…It has poor bioavailability and selectivity [10]. Curcumin is widely used in herbal medicine because it possesses many pharmacological properties [11]. Moreover, as a monotherapy, it exhibits remarkable anti-inflammatory, antioxidant, antimicrobial, and anticarcinogenic effect [12].…”

Section: Introductionmentioning

confidence: 99%

Potential Benefit of Curcumin Adjuvant Therapy to the Standard H. Pylori Eradication Therapy in Patients With Peptic Ulcer Disease

Abdulridha¹,

Abbas

Najeb

2017

Asian J Pharm Clin Res

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Objective: This study was designed to explore the benefit of curcumin as adjuvant therapy to the standard Helicobacter pylori eradication triple therapy in both duodenal and gastric ulcers patients.Methods: The present study enrolled 40 patients newly diagnosed endoscopically with peptic ulcer disease to be allocated into group 1 treated with standard H. pylori eradication triple therapy, and group 2 patients treated with curcumin (500 mg) capsules three times daily for 14 days as an adjuvant to standard triple therapy. Stool antigen test, immunoglobulin M serology test, tumor necrosis factor-alpha (TNF-α), interleukin 1 beta (IL-1β), and total antioxidant capacity (T-AOC) are measured at the baseline and after 6 weeks of treatment. Results:The result showed that the use of curcumin as adjuvant therapy produced highly significant improvement in healing efficacy which was significantly distinguished in duodenal ulcer patients compared to gastric ulcer groups 2 patients (p<0.05), along with a highly significant reduction in pro-inflammatory IL-1β level in group 2 patients (p<0.01). After 6 weeks of treatment, there was a highly significant elevation in the level of TNF-α in groups 1 (p<0.01), though group 2 patients presented with non-significant elevation in TNF-α level. Moreover, the T-AOC was improved with curcumin adjuvant therapy, though non-significant, compared to group 1 patients who showed a reduction in T-AOC. Conclusion:This study revealed that addition of curcumin as adjuvant therapy produced improvement in ulcer healing efficacy, and controlled the inflammatory and oxidative stress process induced by H. pylori infection.

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Cancer—an ayurvedic perspective

Cited by 260 publications

References 48 publications

Herbal Cosmeceuticals for Photoprotection from Ultraviolet B Radiation: A Review

Herbal Cosmeceuticals for Photoprotection from Ultraviolet B Radiation: A Review

Evaluation of Anti-Obesity Activity of Solasodine in High Fat Diet-Induced Obesity in Rat

Potential Benefit of Curcumin Adjuvant Therapy to the Standard H. Pylori Eradication Therapy in Patients With Peptic Ulcer Disease

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